Stigmastanol: Difference between revisions

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'''Stigmastanol''' is a [[phytosterol]], a type of [[sterol]] found in plants. It is a saturated derivative of [[stigmasterol]], which is another plant sterol. Stigmastanol is known for its potential health benefits, particularly in lowering [[cholesterol]] levels and improving [[cardiovascular health]].
{{DISPLAYTITLE:Stigmastanol}}


==Chemical Structure and Properties==
== Overview ==
Stigmastanol has a chemical structure similar to that of [[cholesterol]], which allows it to compete with cholesterol for absorption in the [[digestive system]]. Its chemical formula is C29H52O, and it has a molecular weight of 416.72 g/mol. The structure includes a sterol backbone with a hydroxyl group at the 3-beta position.
'''Stigmastanol''' is a [[phytosterol]], a type of plant sterol that is structurally similar to [[cholesterol]]. It is a saturated derivative of [[stigmasterol]], which is found in various plant sources. Stigmastanol is known for its potential health benefits, particularly in lowering [[cholesterol]] levels in humans.


==Sources==
== Chemical Structure ==
Stigmastanol is found in various plant sources, including [[vegetable oils]], [[nuts]], and [[seeds]]. It is also present in smaller amounts in some fruits and vegetables. The highest concentrations are typically found in unrefined plant oils.
[[File:Stigmastanol.svg|thumb|right|Chemical structure of stigmastanol]]
Stigmastanol has a chemical structure similar to that of cholesterol, with a steroid nucleus and a side chain. The saturation of the side chain distinguishes it from stigmasterol, making it more stable and less prone to oxidation.


==Health Benefits==
== Sources ==
Stigmastanol is primarily studied for its role in lowering [[LDL cholesterol]] levels. By inhibiting the absorption of cholesterol in the intestines, it can help reduce the overall cholesterol levels in the blood. This can lead to a decreased risk of [[atherosclerosis]] and other cardiovascular diseases.
Stigmastanol is found in a variety of plant-based foods, including [[vegetable oils]], [[nuts]], and [[seeds]]. It is also present in some [[cereal]] grains and [[legumes]]. The compound is often extracted and used in [[functional foods]] and [[dietary supplements]] for its cholesterol-lowering properties.


===Cholesterol Reduction===
== Health Benefits ==
Stigmastanol competes with dietary cholesterol for absorption in the intestines. This competition reduces the amount of cholesterol that enters the bloodstream, thereby lowering [[LDL cholesterol]] levels. Studies have shown that regular consumption of stigmastanol can lead to significant reductions in LDL cholesterol.
Stigmastanol is primarily recognized for its ability to lower [[LDL cholesterol]] levels. It competes with cholesterol for absorption in the [[intestine]], thereby reducing the amount of cholesterol that enters the bloodstream. This mechanism can help in the management of [[hypercholesterolemia]] and reduce the risk of [[cardiovascular disease]].


===Cardiovascular Health===
== Mechanism of Action ==
By lowering cholesterol levels, stigmastanol can contribute to improved cardiovascular health. Lower cholesterol levels are associated with a reduced risk of [[heart disease]], [[stroke]], and other cardiovascular conditions.
The primary mechanism by which stigmastanol exerts its effects is through the inhibition of cholesterol absorption in the [[small intestine]]. By competing with dietary and biliary cholesterol for incorporation into [[micelles]], stigmastanol reduces the overall absorption of cholesterol. This leads to a decrease in serum cholesterol levels.


==Uses in Food and Supplements==
== Applications ==
Stigmastanol is often added to [[functional foods]] and dietary supplements aimed at lowering cholesterol. It is commonly found in [[margarines]], [[yogurts]], and other fortified foods. Supplements containing stigmastanol are also available in the form of capsules and tablets.
Stigmastanol is used in the formulation of [[functional foods]] such as [[margarines]], [[yogurts]], and [[milk]] products that are marketed for their cholesterol-lowering effects. It is also available in [[dietary supplements]] aimed at improving cardiovascular health.


==Safety and Side Effects==
== Safety and Side Effects ==
Stigmastanol is generally considered safe for consumption. However, excessive intake may lead to gastrointestinal discomfort, such as bloating and diarrhea. It is important to follow recommended dosages and consult with a healthcare provider before starting any new supplement regimen.
Stigmastanol is generally considered safe for consumption. However, excessive intake may lead to a reduction in the absorption of fat-soluble vitamins such as [[vitamin A]], [[vitamin D]], [[vitamin E]], and [[vitamin K]]. It is important to consume stigmastanol as part of a balanced diet.


==Related Pages==
== Related Pages ==
* [[Phytosterol]]
* [[Phytosterol]]
* [[Cholesterol]]
* [[Stigmasterol]]
* [[Stigmasterol]]
* [[Cholesterol]]
* [[Cardiovascular disease]]
* [[Cardiovascular health]]
* [[LDL cholesterol]]
* [[Functional foods]]


==Categories==
[[Category:Phytosterols]]
[[Category:Phytosterols]]
[[Category:Cardiovascular health]]
[[Category:Nutrition]]
[[Category:Dietary supplements]]
[[Category:Cholesterol]]
 
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Latest revision as of 10:48, 15 February 2025


Overview[edit]

Stigmastanol is a phytosterol, a type of plant sterol that is structurally similar to cholesterol. It is a saturated derivative of stigmasterol, which is found in various plant sources. Stigmastanol is known for its potential health benefits, particularly in lowering cholesterol levels in humans.

Chemical Structure[edit]

File:Stigmastanol.svg
Chemical structure of stigmastanol

Stigmastanol has a chemical structure similar to that of cholesterol, with a steroid nucleus and a side chain. The saturation of the side chain distinguishes it from stigmasterol, making it more stable and less prone to oxidation.

Sources[edit]

Stigmastanol is found in a variety of plant-based foods, including vegetable oils, nuts, and seeds. It is also present in some cereal grains and legumes. The compound is often extracted and used in functional foods and dietary supplements for its cholesterol-lowering properties.

Health Benefits[edit]

Stigmastanol is primarily recognized for its ability to lower LDL cholesterol levels. It competes with cholesterol for absorption in the intestine, thereby reducing the amount of cholesterol that enters the bloodstream. This mechanism can help in the management of hypercholesterolemia and reduce the risk of cardiovascular disease.

Mechanism of Action[edit]

The primary mechanism by which stigmastanol exerts its effects is through the inhibition of cholesterol absorption in the small intestine. By competing with dietary and biliary cholesterol for incorporation into micelles, stigmastanol reduces the overall absorption of cholesterol. This leads to a decrease in serum cholesterol levels.

Applications[edit]

Stigmastanol is used in the formulation of functional foods such as margarines, yogurts, and milk products that are marketed for their cholesterol-lowering effects. It is also available in dietary supplements aimed at improving cardiovascular health.

Safety and Side Effects[edit]

Stigmastanol is generally considered safe for consumption. However, excessive intake may lead to a reduction in the absorption of fat-soluble vitamins such as vitamin A, vitamin D, vitamin E, and vitamin K. It is important to consume stigmastanol as part of a balanced diet.

Related Pages[edit]