Biliary pseudolithiasis: Difference between revisions
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[[File:Biliary_pseudolithiasis.jpg|thumb| | {{SI}} | ||
{{Infobox medical condition | |||
| name = Biliary pseudolithiasis | |||
| image = [[File:Biliary_pseudolithiasis.jpg|left|thumb|Biliary pseudolithiasis]] | |||
| caption = Ultrasound image showing biliary pseudolithiasis | |||
| field = [[Gastroenterology]] | |||
| symptoms = [[Right upper quadrant pain]], [[nausea]], [[vomiting]] | |||
| complications = [[Cholecystitis]], [[pancreatitis]] | |||
| onset = After administration of [[ceftriaxone]] | |||
| duration = Reversible upon discontinuation of the drug | |||
| causes = [[Ceftriaxone]] therapy | |||
| risks = High doses of [[ceftriaxone]], [[pediatric]] patients | |||
| diagnosis = [[Ultrasound]], [[CT scan]] | |||
| differential = [[Cholelithiasis]], [[sludge]] | |||
| prevention = Avoidance of high-dose [[ceftriaxone]] | |||
| treatment = Discontinuation of [[ceftriaxone]] | |||
| prognosis = Excellent with drug discontinuation | |||
| frequency = Rare | |||
}} | |||
[[File:Biliary_pseudolithiasis.jpg|left|thumb]] '''Biliary pseudolithiasis''' is a medical condition characterized by the presence of sludge or sludge-like material in the [[biliary tract]] that mimics the appearance of [[gallstones]] on imaging studies. Unlike true gallstones, biliary pseudolithiasis does not consist of solid calculi but rather of thickened bile or biliary sludge. | |||
==Etiology== | ==Etiology== | ||
Biliary pseudolithiasis is often associated with the use of certain medications, particularly [[ceftriaxone]], a third-generation [[cephalosporin]] antibiotic. The condition can also be seen in patients with [[biliary stasis]], [[total parenteral nutrition]], or other conditions that alter the composition of bile. | Biliary pseudolithiasis is often associated with the use of certain medications, particularly [[ceftriaxone]], a third-generation [[cephalosporin]] antibiotic. The condition can also be seen in patients with [[biliary stasis]], [[total parenteral nutrition]], or other conditions that alter the composition of bile. | ||
==Pathophysiology== | ==Pathophysiology== | ||
The pathophysiology of biliary pseudolithiasis involves the precipitation of bile components, such as [[cholesterol]] crystals, [[bilirubin]] particles, and [[mucin]], forming a sludge-like material. This material can accumulate in the [[gallbladder]] or the [[common bile duct]], leading to symptoms similar to those caused by true gallstones. | The pathophysiology of biliary pseudolithiasis involves the precipitation of bile components, such as [[cholesterol]] crystals, [[bilirubin]] particles, and [[mucin]], forming a sludge-like material. This material can accumulate in the [[gallbladder]] or the [[common bile duct]], leading to symptoms similar to those caused by true gallstones. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
Patients with biliary pseudolithiasis may present with symptoms similar to those of [[cholelithiasis]], including: | Patients with biliary pseudolithiasis may present with symptoms similar to those of [[cholelithiasis]], including: | ||
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* [[Vomiting]] | * [[Vomiting]] | ||
* [[Jaundice]] | * [[Jaundice]] | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of biliary pseudolithiasis is typically made using imaging studies such as [[ultrasonography]] or [[magnetic resonance cholangiopancreatography]] (MRCP). These imaging modalities can reveal the presence of sludge or sludge-like material in the biliary tract. | The diagnosis of biliary pseudolithiasis is typically made using imaging studies such as [[ultrasonography]] or [[magnetic resonance cholangiopancreatography]] (MRCP). These imaging modalities can reveal the presence of sludge or sludge-like material in the biliary tract. | ||
==Management== | ==Management== | ||
Management of biliary pseudolithiasis primarily involves addressing the underlying cause. If the condition is associated with medication use, discontinuation of the offending drug, such as ceftriaxone, may lead to resolution of the pseudolithiasis. In some cases, supportive care and symptomatic treatment may be necessary. | Management of biliary pseudolithiasis primarily involves addressing the underlying cause. If the condition is associated with medication use, discontinuation of the offending drug, such as ceftriaxone, may lead to resolution of the pseudolithiasis. In some cases, supportive care and symptomatic treatment may be necessary. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for patients with biliary pseudolithiasis is generally good, especially if the underlying cause is identified and managed appropriately. The condition is often reversible once the precipitating factor is removed. | The prognosis for patients with biliary pseudolithiasis is generally good, especially if the underlying cause is identified and managed appropriately. The condition is often reversible once the precipitating factor is removed. | ||
==See Also== | ==See Also== | ||
* [[Cholelithiasis]] | * [[Cholelithiasis]] | ||
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* [[Biliary tract]] | * [[Biliary tract]] | ||
* [[Gallbladder]] | * [[Gallbladder]] | ||
==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
==External Links== | ==External Links== | ||
{{Commons category|Biliary pseudolithiasis}} | {{Commons category|Biliary pseudolithiasis}} | ||
[[Category:Hepatology]] | [[Category:Hepatology]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Medicine]] | [[Category:Medicine]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
Latest revision as of 19:23, 4 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Biliary pseudolithiasis | |
|---|---|
 | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Right upper quadrant pain, nausea, vomiting |
| Complications | Cholecystitis, pancreatitis |
| Onset | After administration of ceftriaxone |
| Duration | Reversible upon discontinuation of the drug |
| Types | N/A |
| Causes | Ceftriaxone therapy |
| Risks | High doses of ceftriaxone, pediatric patients |
| Diagnosis | Ultrasound, CT scan |
| Differential diagnosis | Cholelithiasis, sludge |
| Prevention | Avoidance of high-dose ceftriaxone |
| Treatment | Discontinuation of ceftriaxone |
| Medication | N/A |
| Prognosis | Excellent with drug discontinuation |
| Frequency | Rare |
| Deaths | N/A |
Biliary pseudolithiasis is a medical condition characterized by the presence of sludge or sludge-like material in the biliary tract that mimics the appearance of gallstones on imaging studies. Unlike true gallstones, biliary pseudolithiasis does not consist of solid calculi but rather of thickened bile or biliary sludge.
Etiology[edit]
Biliary pseudolithiasis is often associated with the use of certain medications, particularly ceftriaxone, a third-generation cephalosporin antibiotic. The condition can also be seen in patients with biliary stasis, total parenteral nutrition, or other conditions that alter the composition of bile.
Pathophysiology[edit]
The pathophysiology of biliary pseudolithiasis involves the precipitation of bile components, such as cholesterol crystals, bilirubin particles, and mucin, forming a sludge-like material. This material can accumulate in the gallbladder or the common bile duct, leading to symptoms similar to those caused by true gallstones.
Clinical Presentation[edit]
Patients with biliary pseudolithiasis may present with symptoms similar to those of cholelithiasis, including:
Diagnosis[edit]
The diagnosis of biliary pseudolithiasis is typically made using imaging studies such as ultrasonography or magnetic resonance cholangiopancreatography (MRCP). These imaging modalities can reveal the presence of sludge or sludge-like material in the biliary tract.
Management[edit]
Management of biliary pseudolithiasis primarily involves addressing the underlying cause. If the condition is associated with medication use, discontinuation of the offending drug, such as ceftriaxone, may lead to resolution of the pseudolithiasis. In some cases, supportive care and symptomatic treatment may be necessary.
Prognosis[edit]
The prognosis for patients with biliary pseudolithiasis is generally good, especially if the underlying cause is identified and managed appropriately. The condition is often reversible once the precipitating factor is removed.
See Also[edit]
References[edit]
<references group="" responsive="1"></references>
External Links[edit]
