Human genetic enhancement: Difference between revisions

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'''Human genetic enhancement''' refers to the application of [[genetic engineering]] or [[gene therapy]] techniques to the alteration of human beings' [[phenotypic]] traits or capabilities. These alterations can be either somatic (affecting only the individual) or germline (affecting offspring).
{{Short description|Overview of human genetic enhancement}}
{{Use dmy dates|date=October 2023}}


== History ==
==Overview==
[[File:Gene_therapy.jpg|thumb|right|Gene therapy is a key technique in genetic enhancement.]]
'''Human genetic enhancement''' refers to the use of genetic engineering techniques to modify human genes and improve physical, mental, or emotional capacities. This field encompasses a range of technologies, including [[gene therapy]], [[CRISPR-Cas9]] gene editing, and other forms of [[genetic modification]].


The concept of human genetic enhancement has its roots in [[eugenics]], a movement that sought to improve the genetic quality of the human species through selective breeding. However, the modern field of human genetic enhancement emerged in the late 20th century with the advent of [[recombinant DNA]] technology.
==Techniques==


== Techniques ==
===Gene Therapy===
[[Gene therapy]] involves the introduction, removal, or alteration of genetic material within a person's cells to treat or prevent disease. It is a foundational technique in genetic enhancement, aiming to correct defective genes responsible for disease development.


There are several techniques that can be used for human genetic enhancement, including:
===CRISPR-Cas9===
[[CRISPR-Cas9]] is a revolutionary gene-editing technology that allows for precise, directed changes to genomic DNA. It has the potential to correct genetic defects, enhance human capabilities, and even prevent diseases before they manifest.


* '''[[CRISPR]]''': A powerful tool for editing genomes, allowing researchers to easily alter DNA sequences and modify gene function.
===Somatic vs. Germline Enhancement===
* '''[[Gene therapy]]''': A technique that uses genes to treat or prevent disease. This can be done by replacing a mutated gene that causes disease with a healthy copy of the gene, inactivating a mutated gene that is functioning improperly, or introducing a new gene into the body to help fight a disease.
Genetic enhancements can be categorized into [[somatic]] and [[germline]] enhancements. Somatic enhancements target non-reproductive cells and affect only the individual, while germline enhancements involve changes to reproductive cells, potentially affecting future generations.
* '''[[Genetic engineering]]''': The direct manipulation of an organism's genes using biotechnology.


== Ethical considerations ==
==Ethical Considerations==
The ethical implications of human genetic enhancement are significant. Concerns include the potential for [[eugenics]], the exacerbation of social inequalities, and the unforeseen consequences of altering human genetics. Ethical debates focus on the balance between potential benefits and risks, as well as the moral considerations of "playing God."


Human genetic enhancement raises a number of ethical issues, including concerns about [[genetic discrimination]], the potential for a new form of [[eugenics]], and the possibility of creating a genetic underclass. There are also concerns about the safety and efficacy of these techniques, as well as the potential for unforeseen consequences.
==Applications==


== Legal status ==
===Medical Applications===
Genetic enhancement holds promise for treating a variety of genetic disorders, such as [[cystic fibrosis]], [[muscular dystrophy]], and certain types of [[cancer]]. By correcting genetic defects, these technologies can improve quality of life and extend lifespan.


The legal status of human genetic enhancement varies by country. In some countries, such as the [[United States]], certain forms of genetic enhancement are permitted, while in others, such as [[Germany]], they are strictly prohibited.
===Non-Medical Applications===
Beyond medical uses, genetic enhancement could potentially be used to improve physical abilities, cognitive functions, and even emotional well-being. However, these applications raise significant ethical and social concerns.


== See also ==
==Future Prospects==
The future of human genetic enhancement is both promising and uncertain. Advances in [[biotechnology]] and [[genomics]] continue to push the boundaries of what is possible, but societal acceptance and regulatory frameworks will play crucial roles in determining the extent of its application.


* [[Genetic modification]]
==Related pages==
* [[Genetic engineering in science fiction]]
* [[Genetic engineering]]
* [[Designer baby]]
* [[Bioethics]]
* [[Transhumanism]]
* [[Transhumanism]]
 
* [[Human genome]]
== References ==
 
<references />


[[Category:Genetic engineering]]
[[Category:Genetic engineering]]
[[Category:Bioethics]]
[[Category:Bioethics]]
[[Category:Human genetics]]
[[Category:Human genetics]]
{{Genetics-stub}}

Latest revision as of 06:01, 16 February 2025

Overview of human genetic enhancement



Overview[edit]

Gene therapy is a key technique in genetic enhancement.

Human genetic enhancement refers to the use of genetic engineering techniques to modify human genes and improve physical, mental, or emotional capacities. This field encompasses a range of technologies, including gene therapy, CRISPR-Cas9 gene editing, and other forms of genetic modification.

Techniques[edit]

Gene Therapy[edit]

Gene therapy involves the introduction, removal, or alteration of genetic material within a person's cells to treat or prevent disease. It is a foundational technique in genetic enhancement, aiming to correct defective genes responsible for disease development.

CRISPR-Cas9[edit]

CRISPR-Cas9 is a revolutionary gene-editing technology that allows for precise, directed changes to genomic DNA. It has the potential to correct genetic defects, enhance human capabilities, and even prevent diseases before they manifest.

Somatic vs. Germline Enhancement[edit]

Genetic enhancements can be categorized into somatic and germline enhancements. Somatic enhancements target non-reproductive cells and affect only the individual, while germline enhancements involve changes to reproductive cells, potentially affecting future generations.

Ethical Considerations[edit]

The ethical implications of human genetic enhancement are significant. Concerns include the potential for eugenics, the exacerbation of social inequalities, and the unforeseen consequences of altering human genetics. Ethical debates focus on the balance between potential benefits and risks, as well as the moral considerations of "playing God."

Applications[edit]

Medical Applications[edit]

Genetic enhancement holds promise for treating a variety of genetic disorders, such as cystic fibrosis, muscular dystrophy, and certain types of cancer. By correcting genetic defects, these technologies can improve quality of life and extend lifespan.

Non-Medical Applications[edit]

Beyond medical uses, genetic enhancement could potentially be used to improve physical abilities, cognitive functions, and even emotional well-being. However, these applications raise significant ethical and social concerns.

Future Prospects[edit]

The future of human genetic enhancement is both promising and uncertain. Advances in biotechnology and genomics continue to push the boundaries of what is possible, but societal acceptance and regulatory frameworks will play crucial roles in determining the extent of its application.

Related pages[edit]