Azapirone: Difference between revisions
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== Azapirone == | |||
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Latest revision as of 00:52, 20 February 2025
Azapirone is a class of drugs used in the treatment of anxiety disorders and depression. They are commonly known as anxiolytics and have a different mechanism of action compared to other anti-anxiety medications such as benzodiazepines.
Mechanism of Action[edit]
Azapirones work by modulating the serotonin system in the brain. They are partial agonists at the 5-HT1A receptor, which means they stimulate the receptor to a lesser extent than a full agonist. This results in a balance between stimulation and inhibition of the serotonin system, which can help to reduce symptoms of anxiety and depression.
Uses[edit]
Azapirones are primarily used to treat generalized anxiety disorder and panic disorder. They may also be used off-label for other conditions such as social anxiety disorder and post-traumatic stress disorder.
Side Effects[edit]
Common side effects of azapirones include dizziness, headaches, and nausea. In rare cases, they can cause serotonin syndrome, a potentially life-threatening condition characterized by agitation, hallucinations, rapid heartbeat, and high body temperature.
Examples[edit]
Some examples of azapirones include buspirone, gepirone, and ipsapirone. Buspirone is the most commonly prescribed azapirone and is available under the brand name Buspar.
