Lapisteride: Difference between revisions
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{{Short description|Overview of the drug Lapisteride}} | |||
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| image_alt = Chemical structure of Lapisteride | |||
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'''Lapisteride''' is a pharmaceutical compound that functions as a [[5-alpha-reductase inhibitor]]. It is primarily used in the treatment of conditions related to [[androgen]]s, such as [[benign prostatic hyperplasia]] (BPH) and [[androgenic alopecia]]. | |||
Lapisteride works by inhibiting the enzyme [[ | ==Mechanism of Action== | ||
Lapisteride works by inhibiting the enzyme [[5-alpha-reductase]], which is responsible for the conversion of [[testosterone]] into [[dihydrotestosterone]] (DHT). DHT is a potent androgen that plays a significant role in the development and progression of BPH and androgenic alopecia. By reducing the levels of DHT, Lapisteride helps in alleviating the symptoms associated with these conditions. | |||
== Uses == | ==Clinical Uses== | ||
Lapisteride is primarily indicated for the treatment of: | |||
* [[Benign prostatic hyperplasia]]: It helps in reducing the size of the enlarged prostate, thereby improving urinary flow and reducing the risk of urinary retention. | |||
* [[Androgenic alopecia]]: It is used to slow down hair loss and promote hair regrowth in individuals with male pattern baldness. | |||
Lapisteride | ==Side Effects== | ||
Common side effects of Lapisteride include: | |||
* Decreased libido | |||
* Erectile dysfunction | |||
* Ejaculation disorders | |||
These side effects are generally mild and tend to resolve with continued use of the medication. | |||
== | ==Pharmacokinetics== | ||
Lapisteride is well absorbed after oral administration. It undergoes extensive hepatic metabolism and is primarily excreted in the urine. The half-life of Lapisteride allows for once-daily dosing, which enhances patient compliance. | |||
==Contraindications== | |||
Lapisteride is contraindicated in: | |||
* Women who are or may become pregnant, due to the risk of fetal harm. | |||
* Patients with known hypersensitivity to the drug or any of its components. | |||
* [[ | ==Related pages== | ||
* [[5-alpha-reductase inhibitor]] | |||
* [[Benign prostatic hyperplasia]] | * [[Benign prostatic hyperplasia]] | ||
* [[ | * [[Androgenic alopecia]] | ||
* [[Dihydrotestosterone]] | |||
[[Category: | [[Category:5-alpha-reductase inhibitors]] | ||
[[Category:Drugs used in benign prostatic hyperplasia]] | |||
[[Category: | [[Category:Hair loss medications]] | ||
[[Category: | |||
Latest revision as of 18:48, 23 March 2025
Overview of the drug Lapisteride
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Lapisteride is a pharmaceutical compound that functions as a 5-alpha-reductase inhibitor. It is primarily used in the treatment of conditions related to androgens, such as benign prostatic hyperplasia (BPH) and androgenic alopecia.
Mechanism of Action[edit]
Lapisteride works by inhibiting the enzyme 5-alpha-reductase, which is responsible for the conversion of testosterone into dihydrotestosterone (DHT). DHT is a potent androgen that plays a significant role in the development and progression of BPH and androgenic alopecia. By reducing the levels of DHT, Lapisteride helps in alleviating the symptoms associated with these conditions.
Clinical Uses[edit]
Lapisteride is primarily indicated for the treatment of:
- Benign prostatic hyperplasia: It helps in reducing the size of the enlarged prostate, thereby improving urinary flow and reducing the risk of urinary retention.
- Androgenic alopecia: It is used to slow down hair loss and promote hair regrowth in individuals with male pattern baldness.
Side Effects[edit]
Common side effects of Lapisteride include:
- Decreased libido
- Erectile dysfunction
- Ejaculation disorders
These side effects are generally mild and tend to resolve with continued use of the medication.
Pharmacokinetics[edit]
Lapisteride is well absorbed after oral administration. It undergoes extensive hepatic metabolism and is primarily excreted in the urine. The half-life of Lapisteride allows for once-daily dosing, which enhances patient compliance.
Contraindications[edit]
Lapisteride is contraindicated in:
- Women who are or may become pregnant, due to the risk of fetal harm.
- Patients with known hypersensitivity to the drug or any of its components.
