Typical pulmonary carcinoid tumour: Difference between revisions
From WikiMD's Wellness Encyclopedia
CSV import Tags: mobile edit mobile web edit |
CSV import |
||
| Line 1: | Line 1: | ||
{{SI}} | |||
{{Infobox medical condition | |||
File:Lung_carcinoid_-_high_mag.jpg| | | name = Typical pulmonary carcinoid tumour | ||
File:Peripheral_typical_carcinoid_tumor_-_CT_scan_-_Case_266_(8583455406).jpg|Peripheral typical carcinoid tumor - CT scan | | image = [[File:Lung_carcinoid_-_high_mag.jpg|250px]] | ||
File:Lung_carcinoid_-_very_high_mag.jpg|Lung carcinoid - very high magnification | | caption = Micrograph of a typical pulmonary carcinoid tumour | ||
File:Typical_carcinoid_tumor_of_the_lung,_prominent_rosettes.jpg|Typical carcinoid tumor of the lung, prominent rosettes | | field = [[Oncology]] | ||
| synonyms = Typical bronchial carcinoid | |||
| symptoms = [[Cough]], [[hemoptysis]], [[wheezing]], [[dyspnea]] | |||
| complications = [[Metastasis]], [[obstruction]] of airways | |||
| onset = Usually in [[adulthood]] | |||
| duration = Variable | |||
| types = Typical, [[Atypical pulmonary carcinoid tumour|Atypical]] | |||
| causes = Unknown, possibly [[genetic]] | |||
| risks = [[Smoking]], [[family history]] | |||
| diagnosis = [[Biopsy]], [[imaging studies]] | |||
| differential = [[Small cell lung cancer]], [[Adenocarcinoma]], [[Hamartoma]] | |||
| prevention = Avoidance of [[smoking]] | |||
| treatment = [[Surgical resection]], [[chemotherapy]], [[radiation therapy]] | |||
| medication = [[Somatostatin analogs]] | |||
| prognosis = Generally good with treatment | |||
| frequency = Rare, <1% of all [[lung cancer]]s | |||
}} | |||
[[File:Peripheral_typical_carcinoid_tumor_-_CT_scan_-_Case_266_(8583455406).jpg|Peripheral typical carcinoid tumor - CT scan | |||
[[File:Lung_carcinoid_-_very_high_mag.jpg|Lung carcinoid - very high magnification | |||
[[File:Typical_carcinoid_tumor_of_the_lung,_prominent_rosettes.jpg|Typical carcinoid tumor of the lung, prominent rosettes | |||
A '''typical pulmonary carcinoid tumour''' is a type of [[neuroendocrine tumour]] that arises in the [[lungs]]. These tumours are generally considered to be low-grade malignancies and are part of the spectrum of [[lung cancer]]. They are distinct from atypical carcinoid tumours, which have a higher potential for aggressive behavior. | A '''typical pulmonary carcinoid tumour''' is a type of [[neuroendocrine tumour]] that arises in the [[lungs]]. These tumours are generally considered to be low-grade malignancies and are part of the spectrum of [[lung cancer]]. They are distinct from atypical carcinoid tumours, which have a higher potential for aggressive behavior. | ||
=== Pathophysiology === | === Pathophysiology === | ||
Typical pulmonary carcinoid tumours originate from [[neuroendocrine cells]] in the bronchial epithelium. These cells are part of the diffuse neuroendocrine system and have the ability to produce various [[hormones]] and [[neuropeptides]]. The exact cause of these tumours is not well understood, but they are thought to arise from genetic mutations that lead to uncontrolled cell growth. | Typical pulmonary carcinoid tumours originate from [[neuroendocrine cells]] in the bronchial epithelium. These cells are part of the diffuse neuroendocrine system and have the ability to produce various [[hormones]] and [[neuropeptides]]. The exact cause of these tumours is not well understood, but they are thought to arise from genetic mutations that lead to uncontrolled cell growth. | ||
=== Clinical Presentation === | === Clinical Presentation === | ||
Patients with typical pulmonary carcinoid tumours may present with a variety of symptoms, depending on the size and location of the tumour. Common symptoms include: | Patients with typical pulmonary carcinoid tumours may present with a variety of symptoms, depending on the size and location of the tumour. Common symptoms include: | ||
| Line 20: | Line 34: | ||
* [[Dyspnea]] (shortness of breath) | * [[Dyspnea]] (shortness of breath) | ||
* [[Chest pain]] | * [[Chest pain]] | ||
Some patients may be asymptomatic, and the tumour is discovered incidentally on imaging studies performed for other reasons. | Some patients may be asymptomatic, and the tumour is discovered incidentally on imaging studies performed for other reasons. | ||
=== Diagnosis === | === Diagnosis === | ||
The diagnosis of a typical pulmonary carcinoid tumour is typically made through a combination of imaging studies and histological examination. | The diagnosis of a typical pulmonary carcinoid tumour is typically made through a combination of imaging studies and histological examination. | ||
* '''Imaging:''' [[Chest X-ray]] and [[CT scan]] of the chest are commonly used to identify the presence of a mass in the lungs. | * '''Imaging:''' [[Chest X-ray]] and [[CT scan]] of the chest are commonly used to identify the presence of a mass in the lungs. | ||
* '''Biopsy:''' A [[bronchoscopy]] with biopsy or a [[CT-guided needle biopsy]] may be performed to obtain tissue for histological analysis. | * '''Biopsy:''' A [[bronchoscopy]] with biopsy or a [[CT-guided needle biopsy]] may be performed to obtain tissue for histological analysis. | ||
* '''Histology:''' Under the microscope, typical carcinoid tumours are characterized by uniform cells with moderate cytoplasm and round to oval nuclei. They have a low mitotic rate and lack necrosis, distinguishing them from atypical carcinoid tumours. | * '''Histology:''' Under the microscope, typical carcinoid tumours are characterized by uniform cells with moderate cytoplasm and round to oval nuclei. They have a low mitotic rate and lack necrosis, distinguishing them from atypical carcinoid tumours. | ||
=== Treatment === | === Treatment === | ||
The primary treatment for typical pulmonary carcinoid tumours is surgical resection. The type of surgery depends on the size and location of the tumour and may include: | The primary treatment for typical pulmonary carcinoid tumours is surgical resection. The type of surgery depends on the size and location of the tumour and may include: | ||
| Line 35: | Line 45: | ||
* [[Segmentectomy]] | * [[Segmentectomy]] | ||
* [[Wedge resection]] | * [[Wedge resection]] | ||
In cases where surgery is not feasible, other treatments such as [[radiotherapy]] or [[chemotherapy]] may be considered, although these are less effective for typical carcinoid tumours. | In cases where surgery is not feasible, other treatments such as [[radiotherapy]] or [[chemotherapy]] may be considered, although these are less effective for typical carcinoid tumours. | ||
=== Prognosis === | === Prognosis === | ||
The prognosis for patients with typical pulmonary carcinoid tumours is generally favorable, with a high 5-year survival rate. These tumours tend to grow slowly and have a low potential for metastasis compared to other types of lung cancer. | The prognosis for patients with typical pulmonary carcinoid tumours is generally favorable, with a high 5-year survival rate. These tumours tend to grow slowly and have a low potential for metastasis compared to other types of lung cancer. | ||
== See also == | |||
== | |||
* [[Lung cancer]] | * [[Lung cancer]] | ||
* [[Neuroendocrine tumour]] | * [[Neuroendocrine tumour]] | ||
* [[Bronchoscopy]] | * [[Bronchoscopy]] | ||
* [[Lobectomy]] | * [[Lobectomy]] | ||
{{Lung cancer}} | {{Lung cancer}} | ||
{{Neuroendocrine tumors}} | {{Neuroendocrine tumors}} | ||
[[Category:Pulmonary diseases]] | [[Category:Pulmonary diseases]] | ||
[[Category:Neuroendocrine tumors]] | [[Category:Neuroendocrine tumors]] | ||
[[Category:Lung cancer]] | [[Category:Lung cancer]] | ||
Latest revision as of 09:00, 13 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Typical pulmonary carcinoid tumour | |
|---|---|
| |
| Synonyms | Typical bronchial carcinoid |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Cough, hemoptysis, wheezing, dyspnea |
| Complications | Metastasis, obstruction of airways |
| Onset | Usually in adulthood |
| Duration | Variable |
| Types | Typical, Atypical |
| Causes | Unknown, possibly genetic |
| Risks | Smoking, family history |
| Diagnosis | Biopsy, imaging studies |
| Differential diagnosis | Small cell lung cancer, Adenocarcinoma, Hamartoma |
| Prevention | Avoidance of smoking |
| Treatment | Surgical resection, chemotherapy, radiation therapy |
| Medication | Somatostatin analogs |
| Prognosis | Generally good with treatment |
| Frequency | Rare, <1% of all lung cancers |
| Deaths | N/A |
[[File:Peripheral_typical_carcinoid_tumor_-_CT_scan_-_Case_266_(8583455406).jpg|Peripheral typical carcinoid tumor - CT scan
[[File:Lung_carcinoid_-_very_high_mag.jpg|Lung carcinoid - very high magnification
[[File:Typical_carcinoid_tumor_of_the_lung,_prominent_rosettes.jpg|Typical carcinoid tumor of the lung, prominent rosettes
A typical pulmonary carcinoid tumour is a type of neuroendocrine tumour that arises in the lungs. These tumours are generally considered to be low-grade malignancies and are part of the spectrum of lung cancer. They are distinct from atypical carcinoid tumours, which have a higher potential for aggressive behavior.
Pathophysiology[edit]
Typical pulmonary carcinoid tumours originate from neuroendocrine cells in the bronchial epithelium. These cells are part of the diffuse neuroendocrine system and have the ability to produce various hormones and neuropeptides. The exact cause of these tumours is not well understood, but they are thought to arise from genetic mutations that lead to uncontrolled cell growth.
Clinical Presentation[edit]
Patients with typical pulmonary carcinoid tumours may present with a variety of symptoms, depending on the size and location of the tumour. Common symptoms include:
- Cough
- Hemoptysis (coughing up blood)
- Wheezing
- Dyspnea (shortness of breath)
- Chest pain
Some patients may be asymptomatic, and the tumour is discovered incidentally on imaging studies performed for other reasons.
Diagnosis[edit]
The diagnosis of a typical pulmonary carcinoid tumour is typically made through a combination of imaging studies and histological examination.
- Imaging: Chest X-ray and CT scan of the chest are commonly used to identify the presence of a mass in the lungs.
- Biopsy: A bronchoscopy with biopsy or a CT-guided needle biopsy may be performed to obtain tissue for histological analysis.
- Histology: Under the microscope, typical carcinoid tumours are characterized by uniform cells with moderate cytoplasm and round to oval nuclei. They have a low mitotic rate and lack necrosis, distinguishing them from atypical carcinoid tumours.
Treatment[edit]
The primary treatment for typical pulmonary carcinoid tumours is surgical resection. The type of surgery depends on the size and location of the tumour and may include:
In cases where surgery is not feasible, other treatments such as radiotherapy or chemotherapy may be considered, although these are less effective for typical carcinoid tumours.
Prognosis[edit]
The prognosis for patients with typical pulmonary carcinoid tumours is generally favorable, with a high 5-year survival rate. These tumours tend to grow slowly and have a low potential for metastasis compared to other types of lung cancer.
See also[edit]
| Lung cancer | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
This Lung cancer related article is a stub.
|
