AS-19 (drug): Difference between revisions
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== AS-19 (drug) == | |||
[[File:AS-19.svg|thumb|right|Chemical structure of AS-19]] | |||
'''AS-19''' is a selective agonist for the [[5-HT7 receptor]], a subtype of the [[serotonin receptor]] family. It is primarily used in scientific research to study the role of the 5-HT7 receptor in various physiological and neurological processes. | |||
AS-19 is | |||
== | == Pharmacology == | ||
AS-19 exhibits high affinity and selectivity for the 5-HT7 receptor, which is a [[G protein-coupled receptor]] (GPCR) involved in the modulation of [[neurotransmitter]] release, [[circadian rhythm]], and [[thermoregulation]]. The activation of 5-HT7 receptors by AS-19 has been shown to influence [[cognitive function]], [[mood]], and [[sleep-wake cycle]]. | |||
AS-19 | |||
== | == Mechanism of Action == | ||
== | AS-19 acts as an agonist at the 5-HT7 receptor, meaning it binds to the receptor and activates it, mimicking the action of the natural ligand, [[serotonin]]. This activation leads to a cascade of intracellular events, primarily involving the increase of [[cyclic adenosine monophosphate]] (cAMP) levels, which in turn modulates various downstream signaling pathways. | ||
== Research Applications == | |||
AS-19 is utilized in [[neuroscience]] research to explore the therapeutic potential of 5-HT7 receptor modulation in treating [[psychiatric disorders]] such as [[depression]], [[anxiety]], and [[schizophrenia]]. Studies have also investigated its role in [[pain management]] and [[neuroprotection]]. | |||
== Related Pages == | |||
* [[Serotonin receptor]] | * [[Serotonin receptor]] | ||
* [[5- | * [[5-HT7 receptor]] | ||
* [[G protein-coupled receptor]] | |||
* [[Neurotransmitter]] | * [[Neurotransmitter]] | ||
[[Category:Serotonin receptor agonists]] | [[Category:Serotonin receptor agonists]] | ||
[[Category: | [[Category:Research chemicals]] | ||
Latest revision as of 04:03, 13 February 2025
AS-19 (drug)[edit]
AS-19 is a selective agonist for the 5-HT7 receptor, a subtype of the serotonin receptor family. It is primarily used in scientific research to study the role of the 5-HT7 receptor in various physiological and neurological processes.
Pharmacology[edit]
AS-19 exhibits high affinity and selectivity for the 5-HT7 receptor, which is a G protein-coupled receptor (GPCR) involved in the modulation of neurotransmitter release, circadian rhythm, and thermoregulation. The activation of 5-HT7 receptors by AS-19 has been shown to influence cognitive function, mood, and sleep-wake cycle.
Mechanism of Action[edit]
AS-19 acts as an agonist at the 5-HT7 receptor, meaning it binds to the receptor and activates it, mimicking the action of the natural ligand, serotonin. This activation leads to a cascade of intracellular events, primarily involving the increase of cyclic adenosine monophosphate (cAMP) levels, which in turn modulates various downstream signaling pathways.
Research Applications[edit]
AS-19 is utilized in neuroscience research to explore the therapeutic potential of 5-HT7 receptor modulation in treating psychiatric disorders such as depression, anxiety, and schizophrenia. Studies have also investigated its role in pain management and neuroprotection.
