Tulathromycin: Difference between revisions
CSV import |
CSV import |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
== Tulathromycin == | {{Short description|An antibiotic used in veterinary medicine}} | ||
{{Drugbox | |||
| verifiedfields = changed | |||
| verifiedrevid = 477002123 | |||
| image = Tulathromycin.png | |||
| image_size = 250px | |||
| image_alt = Chemical structure of Tulathromycin | |||
}} | |||
'''Tulathromycin''' is a macrolide antibiotic used in veterinary medicine, primarily for the treatment of respiratory diseases in cattle and swine. It is known for its broad-spectrum activity against various bacterial pathogens. | |||
==Pharmacology== | |||
Tulathromycin belongs to the macrolide class of antibiotics, which function by inhibiting bacterial protein synthesis. This is achieved by binding to the 50S subunit of the bacterial ribosome, thereby preventing the translocation of peptides. Tulathromycin is particularly effective against Gram-positive bacteria and some Gram-negative bacteria. | |||
== | ==Uses== | ||
Tulathromycin | Tulathromycin is primarily used in veterinary medicine for the treatment of respiratory diseases in cattle and swine. It is effective against pathogens such as ''[[Mannheimia haemolytica]]'', ''[[Pasteurella multocida]]'', and ''[[Haemophilus parasuis]]''. The drug is administered via injection, allowing for rapid absorption and distribution in the animal's body. | ||
The | ==Mechanism of Action== | ||
The mechanism of action of tulathromycin involves the inhibition of bacterial protein synthesis. By binding to the 50S ribosomal subunit, tulathromycin prevents the elongation of the peptide chain, which is essential for bacterial growth and replication. This action is bacteriostatic, meaning it inhibits the growth of bacteria rather than killing them outright. | |||
== | ==Pharmacokinetics== | ||
Tulathromycin is | Tulathromycin is characterized by its long half-life, which allows for sustained therapeutic concentrations in the animal's body. After administration, it is rapidly absorbed and distributed to the lungs, where it exerts its antibacterial effects. The drug is primarily excreted unchanged in the bile and feces. | ||
== | ==Side Effects== | ||
Common side effects of tulathromycin in animals include mild injection site reactions. In rare cases, animals may experience hypersensitivity reactions. It is important to follow the prescribed dosage and administration guidelines to minimize the risk of adverse effects. | |||
== | ==Regulatory Status== | ||
Tulathromycin is approved for use in veterinary medicine in many countries. It is important to adhere to withdrawal periods before slaughtering animals for food to ensure that drug residues do not enter the human food chain. | |||
==Related pages== | |||
== Related pages == | |||
* [[Macrolide antibiotics]] | * [[Macrolide antibiotics]] | ||
* [[ | * [[Veterinary medicine]] | ||
* [[ | * [[Bacterial respiratory disease]] | ||
[[Category: | [[Category:Macrolide antibiotics]] | ||
[[Category:Veterinary drugs]] | [[Category:Veterinary drugs]] | ||
<gallery> | |||
File:Tulathromycin.png|Tulathromycin | |||
</gallery> | |||
Latest revision as of 01:39, 20 February 2025
An antibiotic used in veterinary medicine
| Tulathromycin | |
|---|---|
| |
| INN | |
| Drug class | |
| Routes of administration | |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | |
| CAS Number | |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| KEGG | |
Tulathromycin is a macrolide antibiotic used in veterinary medicine, primarily for the treatment of respiratory diseases in cattle and swine. It is known for its broad-spectrum activity against various bacterial pathogens.
Pharmacology[edit]
Tulathromycin belongs to the macrolide class of antibiotics, which function by inhibiting bacterial protein synthesis. This is achieved by binding to the 50S subunit of the bacterial ribosome, thereby preventing the translocation of peptides. Tulathromycin is particularly effective against Gram-positive bacteria and some Gram-negative bacteria.
Uses[edit]
Tulathromycin is primarily used in veterinary medicine for the treatment of respiratory diseases in cattle and swine. It is effective against pathogens such as Mannheimia haemolytica, Pasteurella multocida, and Haemophilus parasuis. The drug is administered via injection, allowing for rapid absorption and distribution in the animal's body.
Mechanism of Action[edit]
The mechanism of action of tulathromycin involves the inhibition of bacterial protein synthesis. By binding to the 50S ribosomal subunit, tulathromycin prevents the elongation of the peptide chain, which is essential for bacterial growth and replication. This action is bacteriostatic, meaning it inhibits the growth of bacteria rather than killing them outright.
Pharmacokinetics[edit]
Tulathromycin is characterized by its long half-life, which allows for sustained therapeutic concentrations in the animal's body. After administration, it is rapidly absorbed and distributed to the lungs, where it exerts its antibacterial effects. The drug is primarily excreted unchanged in the bile and feces.
Side Effects[edit]
Common side effects of tulathromycin in animals include mild injection site reactions. In rare cases, animals may experience hypersensitivity reactions. It is important to follow the prescribed dosage and administration guidelines to minimize the risk of adverse effects.
Regulatory Status[edit]
Tulathromycin is approved for use in veterinary medicine in many countries. It is important to adhere to withdrawal periods before slaughtering animals for food to ensure that drug residues do not enter the human food chain.
Related pages[edit]
-
Tulathromycin
