Tutin

Tutin is a naturally occurring toxin found in the plant species Coriaria, particularly Coriaria arborea (Tutu plant), native to New Zealand. It is a potent neurotoxin and has been associated with several cases of poisoning in humans and animals.

Chemical Structure and Properties

Tutin is a sesquiterpene toxin, a class of terpenes that consists of three isoprene units and contains fifteen carbon atoms. Its chemical formula is C15H20O7. It is a white crystalline solid at room temperature and is soluble in water, alcohol, and ether.

Toxicity

Tutin is a potent neurotoxin that affects the central nervous system. It can cause symptoms such as confusion, convulsions, and in severe cases, death. The lethal dose for humans is estimated to be around 4 mg/kg body weight.

Exposure and Treatment

Exposure to tutin can occur through ingestion of honey made from the nectar of Coriaria arborea flowers, or through direct contact with the plant. Treatment for tutin poisoning is primarily supportive, with the aim of managing symptoms and preventing further exposure.

Prevention

Prevention of tutin poisoning involves avoiding consumption of honey from areas where Coriaria arborea is prevalent, and wearing protective clothing when handling the plant.

See Also

• Coriaria
• Neurotoxin
• Sesquiterpene

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