Sucrose intolerance: Difference between revisions
From WikiMD's Wellness Encyclopedia
mNo edit summary |
CSV import |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
{{SI}} | |||
{{Infobox medical condition | |||
| name = Sucrose intolerance | |||
| image = [[File:Sucrose-inkscape.svg|200px]] | |||
| caption = Structure of [[sucrose]] | |||
| synonyms = Congenital sucrase-isomaltase deficiency (CSID), sucrase-isomaltase deficiency | |||
| field = [[Gastroenterology]] | |||
| symptoms = [[Diarrhea]], [[abdominal pain]], [[bloating]], [[gas]] | |||
| onset = Childhood | |||
| duration = Chronic | |||
| causes = Genetic mutation in the [[sucrase-isomaltase]] gene | |||
| risks = [[Family history]] | |||
| diagnosis = [[Breath test]], [[stool acidity test]], [[genetic testing]] | |||
== | | differential = [[Lactose intolerance]], [[fructose malabsorption]], [[irritable bowel syndrome]] | ||
| treatment = [[Dietary management]], [[enzyme replacement therapy]] | |||
Sucrose intolerance is caused by | | medication = [[Sacrosidase]] | ||
| frequency = Rare | |||
}} | |||
{{Short description|Overview of sucrose intolerance}} | |||
'''Sucrose intolerance''', also known as '''congenital sucrase-isomaltase deficiency''' (CSID), is a condition where an individual lacks the enzyme needed to digest [[sucrose]], a common sugar found in many foods. This enzyme deficiency leads to gastrointestinal symptoms when sucrose is consumed. | |||
== Pathophysiology == | |||
Sucrose intolerance is caused by a deficiency in the enzyme [[sucrase-isomaltase]], which is responsible for breaking down sucrose into [[glucose]] and [[fructose]]. This enzyme is located on the brush border of the [[small intestine]]. When sucrase-isomaltase is deficient or absent, sucrose cannot be properly digested, leading to symptoms such as [[diarrhea]], [[abdominal pain]], and [[bloating]]. | |||
== Symptoms == | == Symptoms == | ||
The symptoms of sucrose intolerance can vary in severity and may include: | |||
The symptoms of sucrose intolerance can vary | * Chronic diarrhea | ||
* Abdominal pain and cramping | |||
* Bloating and gas | |||
* Nausea | |||
* Vomiting | |||
These symptoms typically occur after the ingestion of foods containing sucrose. | |||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of sucrose intolerance can be challenging and often involves a combination of dietary history, symptom assessment, and diagnostic tests. Common diagnostic methods include: | |||
* '''Breath hydrogen test''': Measures hydrogen in the breath after ingestion of sucrose. | |||
* '''Sucrose tolerance test''': Monitors blood glucose levels after sucrose ingestion. | |||
== | * '''Genetic testing''': Identifies mutations in the sucrase-isomaltase gene. | ||
== Management == | |||
Management of sucrose intolerance primarily involves dietary modification to limit or avoid sucrose intake. Patients may benefit from: | |||
* '''Sucrose-free diet''': Avoiding foods high in sucrose such as sweets, certain fruits, and processed foods. | |||
* '''Enzyme replacement therapy''': Use of enzyme supplements to aid in the digestion of sucrose. | |||
== Prognosis == | |||
With appropriate dietary management and enzyme supplementation, individuals with sucrose intolerance can lead normal, healthy lives. Early diagnosis and intervention are crucial to prevent complications and improve quality of life. | |||
== See also == | == See also == | ||
* [[Lactose intolerance]] | * [[Lactose intolerance]] | ||
* [[Fructose malabsorption]] | * [[Fructose malabsorption]] | ||
* [[ | * [[Carbohydrate metabolism]] | ||
[[Category:Digestive diseases]] | |||
[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
Latest revision as of 15:48, 12 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Sucrose intolerance | |
|---|---|
| |
| Synonyms | Congenital sucrase-isomaltase deficiency (CSID), sucrase-isomaltase deficiency |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Diarrhea, abdominal pain, bloating, gas |
| Complications | N/A |
| Onset | Childhood |
| Duration | Chronic |
| Types | N/A |
| Causes | Genetic mutation in the sucrase-isomaltase gene |
| Risks | Family history |
| Diagnosis | Breath test, stool acidity test, genetic testing |
| Differential diagnosis | Lactose intolerance, fructose malabsorption, irritable bowel syndrome |
| Prevention | N/A |
| Treatment | Dietary management, enzyme replacement therapy |
| Medication | Sacrosidase |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | N/A |
Overview of sucrose intolerance
Sucrose intolerance, also known as congenital sucrase-isomaltase deficiency (CSID), is a condition where an individual lacks the enzyme needed to digest sucrose, a common sugar found in many foods. This enzyme deficiency leads to gastrointestinal symptoms when sucrose is consumed.
Pathophysiology[edit]
Sucrose intolerance is caused by a deficiency in the enzyme sucrase-isomaltase, which is responsible for breaking down sucrose into glucose and fructose. This enzyme is located on the brush border of the small intestine. When sucrase-isomaltase is deficient or absent, sucrose cannot be properly digested, leading to symptoms such as diarrhea, abdominal pain, and bloating.
Symptoms[edit]
The symptoms of sucrose intolerance can vary in severity and may include:
- Chronic diarrhea
- Abdominal pain and cramping
- Bloating and gas
- Nausea
- Vomiting
These symptoms typically occur after the ingestion of foods containing sucrose.
Diagnosis[edit]
Diagnosis of sucrose intolerance can be challenging and often involves a combination of dietary history, symptom assessment, and diagnostic tests. Common diagnostic methods include:
- Breath hydrogen test: Measures hydrogen in the breath after ingestion of sucrose.
- Sucrose tolerance test: Monitors blood glucose levels after sucrose ingestion.
- Genetic testing: Identifies mutations in the sucrase-isomaltase gene.
Management[edit]
Management of sucrose intolerance primarily involves dietary modification to limit or avoid sucrose intake. Patients may benefit from:
- Sucrose-free diet: Avoiding foods high in sucrose such as sweets, certain fruits, and processed foods.
- Enzyme replacement therapy: Use of enzyme supplements to aid in the digestion of sucrose.
Prognosis[edit]
With appropriate dietary management and enzyme supplementation, individuals with sucrose intolerance can lead normal, healthy lives. Early diagnosis and intervention are crucial to prevent complications and improve quality of life.
