Parasubiculum: Difference between revisions

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==Parasubiculum==


The '''Parasubiculum''' is a region of the brain that is part of the [[hippocampal formation]]. It is located in the [[medial temporal lobe]], adjacent to the [[presubiculum]] and [[subiculum]]. The parasubiculum plays a crucial role in spatial navigation and memory.
{{Infobox brain
| Name            = Parasubiculum
| Latin          =
| Image          =
| Caption        =
| Width          =
| IsPartOf        = [[Hippocampal formation]]
| Artery          =
| Vein            =
| System          = [[Limbic system]]
| Function        =
| NeuroNames      =
| NeuroLexID      =
| MeshName        =
| MeshNumber      =
}}


[[File:Parasubiculum.png|thumb|right|300px|The location of the Parasubiculum in the brain.]]
The '''parasubiculum''' is a component of the [[hippocampal formation]] located in the [[medial temporal lobe]] of the [[brain]]. It is situated adjacent to the [[subiculum]] and plays a role in the processing of [[spatial information]] and [[memory]].


==Structure==
==Structure==
 
The parasubiculum is part of the [[parahippocampal gyrus]] and is located between the [[presubiculum]] and the [[entorhinal cortex]]. It is characterized by a distinct cellular architecture that contributes to its function in the [[limbic system]].
The parasubiculum is a thin, elongated region that is located between the [[presubiculum]] and the [[entorhinal cortex]]. It is composed of three layers: the molecular layer, the pyramidal layer, and the multiform layer. The pyramidal layer contains densely packed [[pyramidal neurons]], which are the primary excitatory neurons in the parasubiculum.


==Function==
==Function==
The parasubiculum is involved in the processing of [[spatial navigation]] and [[memory encoding]]. It receives input from the [[entorhinal cortex]] and projects to the [[hippocampus]], playing a crucial role in the [[hippocampal formation]]'s ability to integrate [[sensory information]] and [[memory processing]].


The parasubiculum is involved in several cognitive functions, including spatial navigation and memory. It receives inputs from the [[entorhinal cortex]], [[presubiculum]], and [[subiculum]], and sends outputs to the [[hippocampus]] and [[entorhinal cortex]]. The parasubiculum is thought to play a role in the transformation of spatial information from a [[egocentric]] to an [[allocentric]] frame of reference.
==Connections==
The parasubiculum has extensive connections with other parts of the [[hippocampal formation]], including the [[subiculum]], [[presubiculum]], and [[entorhinal cortex]]. These connections facilitate the flow of information necessary for [[memory consolidation]] and [[spatial orientation]].


==Clinical significance==
==Clinical significance==
Dysfunction or damage to the parasubiculum can contribute to [[memory disorders]] and [[spatial disorientation]], which are often observed in conditions such as [[Alzheimer's disease]] and other forms of [[dementia]].


Damage to the parasubiculum can result in spatial memory deficits and difficulties with navigation. It has been implicated in several neurological disorders, including [[Alzheimer's disease]] and [[temporal lobe epilepsy]].
==Research==
Recent studies have focused on the role of the parasubiculum in [[neuroplasticity]] and its potential involvement in [[neurodegenerative diseases]]. Understanding its function and connections may provide insights into therapeutic targets for [[cognitive disorders]].


==See also==
==See also==
* [[Hippocampus]]
* [[Hippocampus]]
* [[Subiculum]]
* [[Presubiculum]]
* [[Entorhinal cortex]]
* [[Entorhinal cortex]]
* [[Presubiculum]]
* [[Parahippocampal gyrus]]
* [[Subiculum]]


==References==
==References==
 
{{Reflist}}
{{reflist}}


==External links==
==External links==
* [http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=289 BrainInfo]
* [Link to relevant neuroscience resources]


[[Category:Brain]]
[[Category:Hippocampus]]
[[Category:Neuroanatomy]]
[[Category:Neuroanatomy]]
 
[[Category:Hippocampal formation]]
{{anatomy-stub}}
[[Category:Limbic system]]

Latest revision as of 20:29, 30 December 2024


General Information
Latin
Greek
TA98
TA2
FMA
Details
System Limbic system
Artery
Vein
Nerve
Lymphatic drainage
Precursor
Function
Identifiers
Clinical significance
Notes



The parasubiculum is a component of the hippocampal formation located in the medial temporal lobe of the brain. It is situated adjacent to the subiculum and plays a role in the processing of spatial information and memory.

Structure[edit]

The parasubiculum is part of the parahippocampal gyrus and is located between the presubiculum and the entorhinal cortex. It is characterized by a distinct cellular architecture that contributes to its function in the limbic system.

Function[edit]

The parasubiculum is involved in the processing of spatial navigation and memory encoding. It receives input from the entorhinal cortex and projects to the hippocampus, playing a crucial role in the hippocampal formation's ability to integrate sensory information and memory processing.

Connections[edit]

The parasubiculum has extensive connections with other parts of the hippocampal formation, including the subiculum, presubiculum, and entorhinal cortex. These connections facilitate the flow of information necessary for memory consolidation and spatial orientation.

Clinical significance[edit]

Dysfunction or damage to the parasubiculum can contribute to memory disorders and spatial disorientation, which are often observed in conditions such as Alzheimer's disease and other forms of dementia.

Research[edit]

Recent studies have focused on the role of the parasubiculum in neuroplasticity and its potential involvement in neurodegenerative diseases. Understanding its function and connections may provide insights into therapeutic targets for cognitive disorders.

See also[edit]

References[edit]

<references group="" responsive="1"></references>


External links[edit]

  • [Link to relevant neuroscience resources]