Atypical hyperplasia: Difference between revisions
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{{Infobox medical condition | |||
| name = Atypical hyperplasia | |||
| synonyms = | |||
| field = [[Oncology]], [[Pathology]] | |||
| symptoms = Often asymptomatic, may be detected during [[mammography]] or [[biopsy]] | |||
| complications = Increased risk of [[breast cancer]] | |||
| onset = Typically diagnosed in [[postmenopausal]] women | |||
| duration = Chronic | |||
| causes = Unknown, but associated with [[hormonal]] factors | |||
| risks = Family history of breast cancer, [[hormone replacement therapy]] | |||
| diagnosis = [[Biopsy]], [[histopathology]] | |||
| differential = [[Ductal carcinoma in situ]], [[Lobular carcinoma in situ]] | |||
| prevention = Regular [[screening]], [[lifestyle modification]] | |||
| treatment = [[Surgical excision]], [[chemoprevention]] with [[tamoxifen]] or [[raloxifene]] | |||
| prognosis = Good with treatment, but requires regular monitoring | |||
| frequency = Affects approximately 5-10% of women undergoing breast biopsies | |||
}} | |||
'''Atypical Hyperplasia''' is a medical condition characterized by abnormal growth of cells in the breast or endometrium. It is considered a precancerous condition and is associated with an increased risk of developing [[breast cancer]] or [[endometrial cancer]]. | '''Atypical Hyperplasia''' is a medical condition characterized by abnormal growth of cells in the breast or endometrium. It is considered a precancerous condition and is associated with an increased risk of developing [[breast cancer]] or [[endometrial cancer]]. | ||
==Definition== | ==Definition== | ||
Atypical Hyperplasia refers to the presence of abnormal cells in the breast or endometrium. The term 'atypical' denotes that these cells differ from normal cells in their size, shape, or organization, while 'hyperplasia' indicates an increase in the number of cells. This condition is not cancer, but it can be a forerunner to the onset of breast cancer or endometrial cancer. | Atypical Hyperplasia refers to the presence of abnormal cells in the breast or endometrium. The term 'atypical' denotes that these cells differ from normal cells in their size, shape, or organization, while 'hyperplasia' indicates an increase in the number of cells. This condition is not cancer, but it can be a forerunner to the onset of breast cancer or endometrial cancer. | ||
==Types== | ==Types== | ||
There are two types of Atypical Hyperplasia: Atypical Ductal Hyperplasia (ADH) and Atypical Lobular Hyperplasia (ALH). Both types occur in the breast tissue, but they are distinguished by the location of the abnormal cells. In ADH, the abnormal cells are in the lining of a duct, while in ALH, they are in the lobules. | There are two types of Atypical Hyperplasia: Atypical Ductal Hyperplasia (ADH) and Atypical Lobular Hyperplasia (ALH). Both types occur in the breast tissue, but they are distinguished by the location of the abnormal cells. In ADH, the abnormal cells are in the lining of a duct, while in ALH, they are in the lobules. | ||
==Risk Factors== | ==Risk Factors== | ||
Several risk factors are associated with Atypical Hyperplasia. These include age, family history of breast or endometrial cancer, never having been pregnant, late menopause, and hormone therapy, particularly when estrogen is given without progesterone. | Several risk factors are associated with Atypical Hyperplasia. These include age, family history of breast or endometrial cancer, never having been pregnant, late menopause, and hormone therapy, particularly when estrogen is given without progesterone. | ||
==Diagnosis== | ==Diagnosis== | ||
Atypical Hyperplasia is usually diagnosed through a biopsy, which involves removing a small sample of tissue for examination under a microscope. The biopsy can be performed using a fine needle, a core needle, or through a surgical procedure. | Atypical Hyperplasia is usually diagnosed through a biopsy, which involves removing a small sample of tissue for examination under a microscope. The biopsy can be performed using a fine needle, a core needle, or through a surgical procedure. | ||
==Treatment== | ==Treatment== | ||
The treatment for Atypical Hyperplasia depends on the individual patient's risk factors and the extent of the condition. Options may include careful monitoring, medication, or surgery. | The treatment for Atypical Hyperplasia depends on the individual patient's risk factors and the extent of the condition. Options may include careful monitoring, medication, or surgery. | ||
==Prognosis== | ==Prognosis== | ||
While Atypical Hyperplasia increases the risk of developing breast or endometrial cancer, it does not guarantee that cancer will develop. Regular check-ups and preventive measures can help manage the risk. | While Atypical Hyperplasia increases the risk of developing breast or endometrial cancer, it does not guarantee that cancer will develop. Regular check-ups and preventive measures can help manage the risk. | ||
==See Also== | ==See Also== | ||
* [[Breast Cancer]] | * [[Breast Cancer]] | ||
| Line 24: | Line 35: | ||
* [[Biopsy]] | * [[Biopsy]] | ||
* [[Hormone Therapy]] | * [[Hormone Therapy]] | ||
[[Category:Medical Conditions]] | [[Category:Medical Conditions]] | ||
[[Category:Breast Diseases]] | [[Category:Breast Diseases]] | ||
[[Category:Endometrial Diseases]] | [[Category:Endometrial Diseases]] | ||
{{Medicine-stub}} | {{Medicine-stub}} | ||
{{No image}} | |||
Latest revision as of 22:23, 3 April 2025
| Atypical hyperplasia | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Often asymptomatic, may be detected during mammography or biopsy |
| Complications | Increased risk of breast cancer |
| Onset | Typically diagnosed in postmenopausal women |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown, but associated with hormonal factors |
| Risks | Family history of breast cancer, hormone replacement therapy |
| Diagnosis | Biopsy, histopathology |
| Differential diagnosis | Ductal carcinoma in situ, Lobular carcinoma in situ |
| Prevention | Regular screening, lifestyle modification |
| Treatment | Surgical excision, chemoprevention with tamoxifen or raloxifene |
| Medication | N/A |
| Prognosis | Good with treatment, but requires regular monitoring |
| Frequency | Affects approximately 5-10% of women undergoing breast biopsies |
| Deaths | N/A |
Atypical Hyperplasia is a medical condition characterized by abnormal growth of cells in the breast or endometrium. It is considered a precancerous condition and is associated with an increased risk of developing breast cancer or endometrial cancer.
Definition[edit]
Atypical Hyperplasia refers to the presence of abnormal cells in the breast or endometrium. The term 'atypical' denotes that these cells differ from normal cells in their size, shape, or organization, while 'hyperplasia' indicates an increase in the number of cells. This condition is not cancer, but it can be a forerunner to the onset of breast cancer or endometrial cancer.
Types[edit]
There are two types of Atypical Hyperplasia: Atypical Ductal Hyperplasia (ADH) and Atypical Lobular Hyperplasia (ALH). Both types occur in the breast tissue, but they are distinguished by the location of the abnormal cells. In ADH, the abnormal cells are in the lining of a duct, while in ALH, they are in the lobules.
Risk Factors[edit]
Several risk factors are associated with Atypical Hyperplasia. These include age, family history of breast or endometrial cancer, never having been pregnant, late menopause, and hormone therapy, particularly when estrogen is given without progesterone.
Diagnosis[edit]
Atypical Hyperplasia is usually diagnosed through a biopsy, which involves removing a small sample of tissue for examination under a microscope. The biopsy can be performed using a fine needle, a core needle, or through a surgical procedure.
Treatment[edit]
The treatment for Atypical Hyperplasia depends on the individual patient's risk factors and the extent of the condition. Options may include careful monitoring, medication, or surgery.
Prognosis[edit]
While Atypical Hyperplasia increases the risk of developing breast or endometrial cancer, it does not guarantee that cancer will develop. Regular check-ups and preventive measures can help manage the risk.
