Cimaterol: Difference between revisions

Latest revision as of 03:42, 13 February 2025

A beta-adrenergic agonist used in veterinary medicine

Cimaterol[edit]

Cimaterol is a beta-adrenergic agonist that is primarily used in veterinary medicine to promote muscle growth and improve feed efficiency in livestock. It is a member of the phenethanolamine class of compounds and functions by stimulating beta-adrenergic receptors in the body.

Mechanism of Action[edit]

Cimaterol acts on the beta-2 adrenergic receptors found in muscle tissue. By binding to these receptors, cimaterol activates the adenylate cyclase pathway, leading to an increase in cyclic adenosine monophosphate (cAMP) levels. This cascade results in enhanced protein synthesis and reduced protein degradation, promoting muscle hypertrophy.

Uses in Veterinary Medicine[edit]

Cimaterol is used to enhance the growth rate and feed conversion efficiency in cattle, sheep, and other livestock. It is particularly valued for its ability to increase lean muscle mass while reducing fat deposition. This makes it a useful agent in the production of meat with a higher lean-to-fat ratio.

Safety and Regulation[edit]

The use of cimaterol in food-producing animals is subject to strict regulatory control in many countries. Concerns about residues in meat products and potential adverse effects on human health have led to its regulation. In some regions, the use of cimaterol is prohibited, while in others, it is allowed under specific conditions.

Potential Side Effects[edit]

In animals, cimaterol can cause tachycardia, tremors, and other cardiovascular effects due to its action on beta-adrenergic receptors. Long-term use may lead to receptor desensitization and reduced effectiveness.

Research and Development[edit]

Research into cimaterol and other beta-adrenergic agonists continues, with studies focusing on optimizing their use in agriculture and understanding their pharmacokinetics and pharmacodynamics.

Related pages[edit]

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-'''Cimaterol''' is a [[beta-adrenergic agonist]] that is used in the [[livestock]] industry to increase the [[lean meat]] yield in animals. It is part of a class of drugs known as [[beta-agonists]], which are used to stimulate [[beta-adrenoceptor]]s in various tissues in the body.
+{{Short description|A beta-adrenergic agonist used in veterinary medicine}}
-== History ==
+==Cimaterol==
-Cimaterol was first developed in the 1980s as a growth promoter for livestock. It was found to increase the lean meat yield in animals, making it a valuable tool for the livestock industry. However, concerns about potential health risks led to its ban in several countries, including the [[European Union]] and [[Canada]].
+[[File:Cimaterol.svg|thumb|right|Chemical structure of Cimaterol]]
+'''Cimaterol''' is a [[beta-adrenergic agonist]] that is primarily used in [[veterinary medicine]] to promote [[muscle growth]] and improve [[feed efficiency]] in [[livestock]]. It is a member of the [[phenethanolamine]] class of compounds and functions by stimulating [[beta-adrenergic receptors]] in the body.
-== Mechanism of Action ==
+==Mechanism of Action==
-Cimaterol works by binding to beta-adrenoceptors in muscle and fat tissue. This stimulates the breakdown of fat and the growth of muscle tissue, leading to an increase in lean meat yield. The drug is typically administered in the feed of animals, allowing it to be absorbed into the bloodstream and exert its effects.
+Cimaterol acts on the [[beta-2 adrenergic receptor|beta-2 adrenergic receptors]] found in [[muscle tissue]]. By binding to these receptors, cimaterol activates the [[adenylate cyclase]] pathway, leading to an increase in [[cyclic adenosine monophosphate]] (cAMP) levels. This cascade results in enhanced [[protein synthesis]] and reduced [[protein degradation]], promoting [[muscle hypertrophy]].
-== Side Effects ==
+==Uses in Veterinary Medicine==
-While cimaterol is effective at increasing lean meat yield, it can also have a number of side effects. These can include increased heart rate, tremors, and restlessness. In some cases, it can also lead to a condition known as [[pulmonary edema]], which is a buildup of fluid in the lungs.
+Cimaterol is used to enhance the [[growth rate]] and [[feed conversion efficiency]] in [[cattle]], [[sheep]], and other [[livestock]]. It is particularly valued for its ability to increase [[lean muscle mass]] while reducing [[fat deposition]]. This makes it a useful agent in the production of [[meat]] with a higher [[lean-to-fat ratio]].
-== Legal Status ==
+==Safety and Regulation==
-Cimaterol is currently banned in several countries due to concerns about its potential health risks. However, it is still used in some countries, including the [[United States]], where it is regulated by the [[Food and Drug Administration]].
+The use of cimaterol in [[food-producing animals]] is subject to strict [[regulatory control]] in many countries. Concerns about [[residue]]s in [[meat products]] and potential [[adverse effects]] on [[human health]] have led to its regulation. In some regions, the use of cimaterol is prohibited, while in others, it is allowed under specific conditions.
-== See Also ==
+==Potential Side Effects==
-* [[Beta-agonist]]
+In animals, cimaterol can cause [[tachycardia]], [[tremors]], and other [[cardiovascular effects]] due to its action on beta-adrenergic receptors. Long-term use may lead to [[receptor desensitization]] and reduced effectiveness.
-* [[Livestock]]
-* [[Lean meat]]
-* [[Pulmonary edema]]
-[[Category:Drugs]]
+==Research and Development==
-[[Category:Livestock]]
+Research into cimaterol and other beta-adrenergic agonists continues, with studies focusing on optimizing their use in [[agriculture]] and understanding their [[pharmacokinetics]] and [[pharmacodynamics]].
-[[Category:Meat]]
-{{stub}}
+==Related pages==
+* [[Beta-adrenergic agonist]]
+* [[Veterinary medicine]]
+* [[Muscle hypertrophy]]
+* [[Feed efficiency]]
+[[Category:Beta-adrenergic agonists]]
+[[Category:Veterinary drugs]]