Unstable angina: Difference between revisions

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'''Unstable angina''' is a condition that is characterized by chest pain or discomfort due to coronary heart disease. It occurs when the heart muscle doesn't get as much blood (and thus oxygen) as it needs. This usually happens because one or more of the heart's arteries is narrowed or blocked, also known as ischemia.
{{SI}}
 
{{Infobox medical condition
== Causes ==
| name                    = Unstable angina
Unstable angina is caused by the formation of a blood clot that partially or totally blocks an artery in the heart. The most common cause is atherosclerosis, a disease in which a fatty material called plaque builds up on the inner walls of the coronary arteries. Other causes include blood clots, coronary artery spasm, or extreme physical exertion.
| image                  = [[File:A_man_having_a_Heart_Attack.png|250px]]
 
| caption                = Illustration of a man experiencing a heart attack
== Symptoms ==
| field                  = [[Cardiology]]
The symptoms of unstable angina are similar to those of a heart attack and may include chest pain or discomfort, which may travel from the chest to the jaw, neck, arms, back or even the teeth. The patient may also experience shortness of breath, sweating, dizziness, nausea, and fatigue.
| synonyms                = Crescendo angina, preinfarction angina
 
| symptoms                = [[Chest pain]], [[shortness of breath]], [[nausea]], [[sweating]]
== Diagnosis ==
| complications          = [[Myocardial infarction]], [[heart failure]], [[arrhythmia]]
The diagnosis of unstable angina is made based on the patient's medical history, a physical examination, and several tests. These tests may include an electrocardiogram (ECG), blood tests, a chest X-ray, a coronary angiogram, or a stress test.
| onset                  = Sudden
 
| duration                = Variable
== Treatment ==
| causes                  = [[Coronary artery disease]], [[atherosclerosis]]
The treatment of unstable angina includes medications to reduce the heart's demand for oxygen and to prevent blood clots from forming. It may also include a procedure to restore blood flow to the heart, such as angioplasty and stenting, or coronary artery bypass surgery.
| risks                  = [[Smoking]], [[hypertension]], [[diabetes mellitus]], [[hyperlipidemia]], [[family history of heart disease]]
 
| diagnosis              = [[Electrocardiogram]], [[blood tests]] (e.g., [[troponin]]), [[coronary angiography]]
== Prognosis ==
| differential            = [[Stable angina]], [[myocardial infarction]], [[pericarditis]], [[pulmonary embolism]]
The prognosis for unstable angina is generally good with treatment. However, it is a serious condition that needs immediate medical attention and can lead to a heart attack or cardiac arrest if not treated promptly.
| prevention              = [[Lifestyle modification]], [[medication]]
 
| treatment              = [[Medication]], [[percutaneous coronary intervention]], [[coronary artery bypass grafting]]
== See also ==
| medication              = [[Nitrates]], [[beta blockers]], [[antiplatelet drugs]], [[statins]]
| prognosis              = Variable, depends on treatment and risk factors
| frequency              = Common
| deaths                  = Significant cause of [[cardiovascular mortality]]
}}
{{short description|A type of angina pectoris that is irregular and unpredictable}}
'''Unstable angina''' is a condition characterized by unexpected chest pain, often occurring at rest, and is a form of [[acute coronary syndrome]]. It is considered a medical emergency because it can precede a [[myocardial infarction]] (heart attack). Unlike [[stable angina]], which occurs predictably with exertion, unstable angina is unpredictable and can occur without any apparent trigger.
==Pathophysiology==
Unstable angina is primarily caused by the rupture of an [[atherosclerotic plaque]] in a coronary artery, leading to partial obstruction of blood flow. This results in insufficient [[oxygen]] supply to the [[myocardium]], causing ischemia and chest pain. The condition is often associated with [[thrombosis]] and [[inflammation]] within the coronary arteries.
==Symptoms==
The primary symptom of unstable angina is chest pain or discomfort, which may radiate to the [[shoulder]], [[arm]], [[back]], [[neck]], or [[jaw]]. The pain is often described as a pressure or squeezing sensation. Other symptoms may include:
* [[Dyspnea]] (shortness of breath)
* [[Nausea]]
* [[Diaphoresis]] (sweating)
* [[Dizziness]] or [[lightheadedness]]
==Diagnosis==
Diagnosis of unstable angina involves a combination of clinical evaluation, [[electrocardiogram]] (ECG) findings, and [[biomarker]] analysis. Unlike a myocardial infarction, unstable angina does not typically result in elevated cardiac biomarkers such as [[troponin]]. However, ECG changes such as [[ST-segment depression]] or [[T-wave inversion]] may be present.
==Treatment==
The management of unstable angina involves both pharmacological and non-pharmacological strategies. Immediate treatment aims to relieve symptoms and prevent progression to myocardial infarction. Common treatments include:
* [[Nitrates]] to relieve chest pain
* [[Antiplatelet therapy]] such as [[aspirin]] and [[clopidogrel]]
* [[Anticoagulants]] like [[heparin]]
* [[Beta-blockers]] to reduce myocardial oxygen demand
* [[Statins]] to stabilize atherosclerotic plaques
In some cases, [[revascularization]] procedures such as [[percutaneous coronary intervention]] (PCI) or [[coronary artery bypass grafting]] (CABG) may be necessary.
==Prognosis==
The prognosis of unstable angina varies depending on the severity of the condition and the effectiveness of treatment. Early intervention and management can significantly improve outcomes and reduce the risk of progression to myocardial infarction.
==See also==
* [[Angina pectoris]]
* [[Angina pectoris]]
* [[Myocardial infarction]]
* [[Coronary artery disease]]
* [[Coronary artery disease]]
* [[Heart attack]]
* [[Acute coronary syndrome]]
* [[Ischemic heart disease]]
 
== References ==
<references />
 
[[Category:Cardiology]]
[[Category:Cardiology]]
[[Category:Angina]]
[[Category:Medical emergencies]]
[[Category:Coronary artery disease]]
[[Category:Heart diseases]]
{{stub}}

Latest revision as of 06:03, 6 April 2025

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Unstable angina
File:A man having a Heart Attack.png
Synonyms Crescendo angina, preinfarction angina
Pronounce N/A
Specialty N/A
Symptoms Chest pain, shortness of breath, nausea, sweating
Complications Myocardial infarction, heart failure, arrhythmia
Onset Sudden
Duration Variable
Types N/A
Causes Coronary artery disease, atherosclerosis
Risks Smoking, hypertension, diabetes mellitus, hyperlipidemia, family history of heart disease
Diagnosis Electrocardiogram, blood tests (e.g., troponin), coronary angiography
Differential diagnosis Stable angina, myocardial infarction, pericarditis, pulmonary embolism
Prevention Lifestyle modification, medication
Treatment Medication, percutaneous coronary intervention, coronary artery bypass grafting
Medication Nitrates, beta blockers, antiplatelet drugs, statins
Prognosis Variable, depends on treatment and risk factors
Frequency Common
Deaths Significant cause of cardiovascular mortality


A type of angina pectoris that is irregular and unpredictable


Unstable angina is a condition characterized by unexpected chest pain, often occurring at rest, and is a form of acute coronary syndrome. It is considered a medical emergency because it can precede a myocardial infarction (heart attack). Unlike stable angina, which occurs predictably with exertion, unstable angina is unpredictable and can occur without any apparent trigger.

Pathophysiology[edit]

Unstable angina is primarily caused by the rupture of an atherosclerotic plaque in a coronary artery, leading to partial obstruction of blood flow. This results in insufficient oxygen supply to the myocardium, causing ischemia and chest pain. The condition is often associated with thrombosis and inflammation within the coronary arteries.

Symptoms[edit]

The primary symptom of unstable angina is chest pain or discomfort, which may radiate to the shoulder, arm, back, neck, or jaw. The pain is often described as a pressure or squeezing sensation. Other symptoms may include:

Diagnosis[edit]

Diagnosis of unstable angina involves a combination of clinical evaluation, electrocardiogram (ECG) findings, and biomarker analysis. Unlike a myocardial infarction, unstable angina does not typically result in elevated cardiac biomarkers such as troponin. However, ECG changes such as ST-segment depression or T-wave inversion may be present.

Treatment[edit]

The management of unstable angina involves both pharmacological and non-pharmacological strategies. Immediate treatment aims to relieve symptoms and prevent progression to myocardial infarction. Common treatments include:

In some cases, revascularization procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) may be necessary.

Prognosis[edit]

The prognosis of unstable angina varies depending on the severity of the condition and the effectiveness of treatment. Early intervention and management can significantly improve outcomes and reduce the risk of progression to myocardial infarction.

See also[edit]