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'''National Cancer Institute''' ('''NCI''') is a part of the [[National Institutes of Health]] (NIH), which is one of eleven agencies that are part of the [[U.S. Department of Health and Human Services]]. The NCI coordinates the [[United States]] National Cancer Program and conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of [[cancer]]; the supportive care of cancer patients and their families; and cancer survivorship.
{{short description|United States government agency for cancer research}}
{{Use American English|date=October 2023}}
{{Use mdy dates|date=October 2023}}
 
[[File:National_Cancer_Institute_logo.svg|thumb|right|The official logo of the National Cancer Institute]]
 
The '''National Cancer Institute''' ('''NCI''') is part of the [[United States Department of Health and Human Services]] and is one of the 27 institutes and centers that comprise the [[National Institutes of Health]] (NIH). The NCI coordinates the U.S. National Cancer Program and conducts and supports research, training, health information dissemination, and other programs with respect to the cause, diagnosis, prevention, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients.


==History==
==History==
The National Cancer Institute was established by Congress in 1937 as the federal government's principal agency to conduct research on cancer, its causes, and treatments. The NCI became a component of the National Institutes of Health in 1944.
[[File:NIH_building_6_groundbreaking.jpg|thumb|left|Groundbreaking ceremony for NIH Building 6, an important site for cancer research]]
The National Cancer Institute was established by the [[National Cancer Act of 1937]], signed into law by President [[Franklin D. Roosevelt]]. It was the first time Congress had appropriated funds toward a non-communicable disease. The NCI was initially part of the [[Public Health Service]] and was later incorporated into the NIH in 1944.
 
The NCI has played a pivotal role in cancer research and treatment development. In the 1950s and 1960s, the NCI supported the development of chemotherapy drugs such as [[Cyclophosphamide]], [[Vincristine]], and [[Carboplatin]].


==Mission==
==Research and Programs==
The mission of the NCI is to lead, conduct, and support cancer research across the nation to advance scientific knowledge and help all people live longer, healthier lives. Its mission is accomplished through a comprehensive program of research, training, and information dissemination.
The NCI conducts its own research through the [[NCI Intramural Research Program]] and funds cancer research at universities and other institutions through its [[NCI Extramural Research Program]].


==Research==
===Intramural Research===
The NCI conducts and supports a broad range of research, from basic research to clinical trials, to understand the causes of cancer and to develop strategies for its prevention, diagnosis, and treatment. The NCI also supports the training of scientists and health care providers.
The NCI's intramural research program is conducted at the NIH campus in [[Bethesda, Maryland]], and at the NCI-Frederick campus in [[Frederick, Maryland]]. This program includes basic, translational, and clinical research.


==See also==
===Extramural Research===
* [[Cancer]]
The NCI funds a wide range of cancer research projects across the United States and internationally. This includes funding for [[Cancer Centers]], [[Specialized Programs of Research Excellence]] (SPOREs), and [[Research Project Grants]].
* [[National Institutes of Health]]
 
* [[U.S. Department of Health and Human Services]]
==Cancer Centers Program==
The NCI Cancer Centers Program is a cornerstone of the NCI's efforts to reduce the burden of cancer. There are currently 71 NCI-designated Cancer Centers, which are recognized for their scientific leadership, resources, and the depth and breadth of their research in basic, clinical, and population science.
 
==Leadership==
[[File:Portrait_photo_of_Carl_Voegtlin.jpg|thumb|right|Carl Voegtlin, the first director of the NCI]]
The NCI is led by a director who is appointed by the President of the United States. The first director of the NCI was [[Carl Voegtlin]], who served from 1938 to 1943. The current director is [[Norman E. Sharpless]], who has been in office since 2017.


==References==
==Notable Contributions==
<references />
[[File:Cyclophosphamide_structure.svg|thumb|left|Structure of Cyclophosphamide, a chemotherapy drug developed with NCI support]]
The NCI has been instrumental in the development of many cancer treatments and has contributed to significant advances in cancer research. Notable contributions include the development of chemotherapy agents such as Cyclophosphamide, Vincristine, and Carboplatin.


==External links==
==Related pages==
* [https://www.cancer.gov/ Official website]
* [[National Institutes of Health]]
* [[Cancer research]]
* [[Chemotherapy]]
* [[Oncology]]


[[Category:National Institutes of Health]]
[[Category:National Institutes of Health]]
[[Category:Cancer organizations]]
[[Category:Cancer organizations based in the United States]]
[[Category:Medical research institutes in the United States]]
[[Category:Medical research institutes in Maryland]]
[[Category:1937 establishments in the United States]]
[[Category:Research institutes in the United States]]
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Latest revision as of 11:15, 23 March 2025

United States government agency for cancer research



The official logo of the National Cancer Institute

The National Cancer Institute (NCI) is part of the United States Department of Health and Human Services and is one of the 27 institutes and centers that comprise the National Institutes of Health (NIH). The NCI coordinates the U.S. National Cancer Program and conducts and supports research, training, health information dissemination, and other programs with respect to the cause, diagnosis, prevention, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients.

History[edit]

Groundbreaking ceremony for NIH Building 6, an important site for cancer research

The National Cancer Institute was established by the National Cancer Act of 1937, signed into law by President Franklin D. Roosevelt. It was the first time Congress had appropriated funds toward a non-communicable disease. The NCI was initially part of the Public Health Service and was later incorporated into the NIH in 1944.

The NCI has played a pivotal role in cancer research and treatment development. In the 1950s and 1960s, the NCI supported the development of chemotherapy drugs such as Cyclophosphamide, Vincristine, and Carboplatin.

Research and Programs[edit]

The NCI conducts its own research through the NCI Intramural Research Program and funds cancer research at universities and other institutions through its NCI Extramural Research Program.

Intramural Research[edit]

The NCI's intramural research program is conducted at the NIH campus in Bethesda, Maryland, and at the NCI-Frederick campus in Frederick, Maryland. This program includes basic, translational, and clinical research.

Extramural Research[edit]

The NCI funds a wide range of cancer research projects across the United States and internationally. This includes funding for Cancer Centers, Specialized Programs of Research Excellence (SPOREs), and Research Project Grants.

Cancer Centers Program[edit]

The NCI Cancer Centers Program is a cornerstone of the NCI's efforts to reduce the burden of cancer. There are currently 71 NCI-designated Cancer Centers, which are recognized for their scientific leadership, resources, and the depth and breadth of their research in basic, clinical, and population science.

Leadership[edit]

Carl Voegtlin, the first director of the NCI

The NCI is led by a director who is appointed by the President of the United States. The first director of the NCI was Carl Voegtlin, who served from 1938 to 1943. The current director is Norman E. Sharpless, who has been in office since 2017.

Notable Contributions[edit]

Structure of Cyclophosphamide, a chemotherapy drug developed with NCI support

The NCI has been instrumental in the development of many cancer treatments and has contributed to significant advances in cancer research. Notable contributions include the development of chemotherapy agents such as Cyclophosphamide, Vincristine, and Carboplatin.

Related pages[edit]