Endodermal sinus tumor: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Endodermal sinus tumor | |||
| image = [[File:Mixed_germ_cell_tumour_-_high_mag.jpg|left|thumb|Endodermal sinus tumor under microscope]] | |||
| caption = Histopathological image of an endodermal sinus tumor | |||
| field = [[Oncology]] | |||
| synonyms = Yolk sac tumor | |||
| symptoms = Abdominal pain, swelling, [[ascites]], [[dyspnea]] | |||
| complications = [[Metastasis]], [[infertility]] | |||
| onset = Typically in children and young adults | |||
| duration = Variable | |||
| causes = Unknown, associated with [[germ cell tumors]] | |||
| risks = [[Cryptorchidism]], [[genetic predisposition]] | |||
| diagnosis = [[Histopathology]], [[tumor markers]] | |||
| differential = [[Teratoma]], [[embryonal carcinoma]], [[choriocarcinoma]] | |||
| prevention = None known | |||
| treatment = [[Surgery]], [[chemotherapy]] | |||
| medication = [[Cisplatin]], [[etoposide]], [[bleomycin]] | |||
| prognosis = Generally good with treatment | |||
| frequency = Rare | |||
| deaths = Varies depending on stage and treatment | |||
}} | |||
[[File:Histopathology_of_endodermal_sinus_tumor_with_Schiller–Duval_bodies.png|Histopathology of endodermal sinus tumor with Schiller–Duval bodies|thumb|left]] | |||
'''Endodermal sinus tumor''' (EST) is a rare, aggressive type of [[germ cell tumor]] that typically originates in the [[ovaries]] or [[testes]]. It is also known as '''yolk sac tumor''' due to its resemblance to the yolk sac of an early human embryo. This tumor is most commonly diagnosed in children and young adults. | '''Endodermal sinus tumor''' (EST) is a rare, aggressive type of [[germ cell tumor]] that typically originates in the [[ovaries]] or [[testes]]. It is also known as '''yolk sac tumor''' due to its resemblance to the yolk sac of an early human embryo. This tumor is most commonly diagnosed in children and young adults. | ||
== Symptoms == | == Symptoms == | ||
The symptoms of an endodermal sinus tumor can vary depending on the location of the tumor. Common symptoms include abdominal or pelvic pain, a palpable mass, and unexplained weight loss. In males, the tumor may cause testicular swelling or discomfort. | The symptoms of an endodermal sinus tumor can vary depending on the location of the tumor. Common symptoms include abdominal or pelvic pain, a palpable mass, and unexplained weight loss. In males, the tumor may cause testicular swelling or discomfort. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of an endodermal sinus tumor typically involves a combination of physical examination, imaging studies such as [[Ultrasound|ultrasound]] or [[Computed tomography|CT scan]], and laboratory tests. A definitive diagnosis is usually made through a [[Biopsy|biopsy]] of the tumor. | Diagnosis of an endodermal sinus tumor typically involves a combination of physical examination, imaging studies such as [[Ultrasound|ultrasound]] or [[Computed tomography|CT scan]], and laboratory tests. A definitive diagnosis is usually made through a [[Biopsy|biopsy]] of the tumor. | ||
== Treatment == | == Treatment == | ||
Treatment for endodermal sinus tumor often involves a combination of [[Surgery|surgery]], [[Chemotherapy|chemotherapy]], and [[Radiation therapy|radiation therapy]]. The choice of treatment depends on the size and location of the tumor, the patient's overall health, and whether the cancer has spread to other parts of the body. | Treatment for endodermal sinus tumor often involves a combination of [[Surgery|surgery]], [[Chemotherapy|chemotherapy]], and [[Radiation therapy|radiation therapy]]. The choice of treatment depends on the size and location of the tumor, the patient's overall health, and whether the cancer has spread to other parts of the body. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for patients with endodermal sinus tumor varies widely and depends on several factors, including the stage of the disease at diagnosis, the patient's age and overall health, and the response to treatment. | The prognosis for patients with endodermal sinus tumor varies widely and depends on several factors, including the stage of the disease at diagnosis, the patient's age and overall health, and the response to treatment. | ||
== See also == | == See also == | ||
* [[Germ cell tumor]] | * [[Germ cell tumor]] | ||
* [[Ovarian cancer]] | * [[Ovarian cancer]] | ||
* [[Testicular cancer]] | * [[Testicular cancer]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Pediatrics]] | [[Category:Pediatrics]] | ||
[[Category:Gynecology]] | [[Category:Gynecology]] | ||
[[Category:Urology]] | [[Category:Urology]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 16:14, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Endodermal sinus tumor | |
|---|---|
 | |
| Synonyms | Yolk sac tumor |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abdominal pain, swelling, ascites, dyspnea |
| Complications | Metastasis, infertility |
| Onset | Typically in children and young adults |
| Duration | Variable |
| Types | N/A |
| Causes | Unknown, associated with germ cell tumors |
| Risks | Cryptorchidism, genetic predisposition |
| Diagnosis | Histopathology, tumor markers |
| Differential diagnosis | Teratoma, embryonal carcinoma, choriocarcinoma |
| Prevention | None known |
| Treatment | Surgery, chemotherapy |
| Medication | Cisplatin, etoposide, bleomycin |
| Prognosis | Generally good with treatment |
| Frequency | Rare |
| Deaths | Varies depending on stage and treatment |
Endodermal sinus tumor (EST) is a rare, aggressive type of germ cell tumor that typically originates in the ovaries or testes. It is also known as yolk sac tumor due to its resemblance to the yolk sac of an early human embryo. This tumor is most commonly diagnosed in children and young adults.
Symptoms[edit]
The symptoms of an endodermal sinus tumor can vary depending on the location of the tumor. Common symptoms include abdominal or pelvic pain, a palpable mass, and unexplained weight loss. In males, the tumor may cause testicular swelling or discomfort.
Diagnosis[edit]
Diagnosis of an endodermal sinus tumor typically involves a combination of physical examination, imaging studies such as ultrasound or CT scan, and laboratory tests. A definitive diagnosis is usually made through a biopsy of the tumor.
Treatment[edit]
Treatment for endodermal sinus tumor often involves a combination of surgery, chemotherapy, and radiation therapy. The choice of treatment depends on the size and location of the tumor, the patient's overall health, and whether the cancer has spread to other parts of the body.
Prognosis[edit]
The prognosis for patients with endodermal sinus tumor varies widely and depends on several factors, including the stage of the disease at diagnosis, the patient's age and overall health, and the response to treatment.
See also[edit]
References[edit]
<references />
