Porocarcinoma: Difference between revisions
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{{Infobox medical condition | |||
[[File:Porocarcinoma_-_alt_--_low_mag.jpg| | | name = Porocarcinoma | ||
| image = [[File:Porocarcinoma_-_alt_--_low_mag.jpg|alt=Porocarcinoma under low magnification]] | |||
| caption = Porocarcinoma under low magnification | |||
| synonyms = Malignant eccrine poroma, eccrine porocarcinoma | |||
| specialty = [[Dermatology]], [[Oncology]] | |||
| symptoms = [[Skin lesion]], [[ulceration]], [[bleeding]] | |||
| onset = Typically in [[adulthood]] | |||
| duration = [[Chronic (medicine)|Chronic]] | |||
| causes = [[Genetic mutations]], [[UV radiation]] | |||
| risks = [[Sun exposure]], [[immunosuppression]] | |||
| diagnosis = [[Biopsy]], [[histopathology]] | |||
| differential = [[Squamous cell carcinoma]], [[basal cell carcinoma]], [[melanoma]] | |||
| treatment = [[Surgical excision]], [[radiation therapy]], [[chemotherapy]] | |||
| prognosis = Variable, depends on stage and treatment | |||
| frequency = Rare | |||
}} | |||
'''Porocarcinoma''', also known as eccrine porocarcinoma, is a rare type of [[skin cancer]] that originates from the [[eccrine sweat gland]]s. It is considered a [[malignant]] form of [[poroma]], a benign sweat gland tumor. Porocarcinoma is most commonly found in the elderly population and can occur anywhere on the body, although it frequently appears on the lower extremities. | '''Porocarcinoma''', also known as eccrine porocarcinoma, is a rare type of [[skin cancer]] that originates from the [[eccrine sweat gland]]s. It is considered a [[malignant]] form of [[poroma]], a benign sweat gland tumor. Porocarcinoma is most commonly found in the elderly population and can occur anywhere on the body, although it frequently appears on the lower extremities. | ||
== Clinical Presentation == | == Clinical Presentation == | ||
Porocarcinoma typically presents as a solitary, slow-growing [[nodule]] or [[plaque]] that may be [[ulcerated]] or [[bleeding]]. The lesion can vary in color, appearing as red, pink, or brown. Due to its nonspecific appearance, porocarcinoma can be mistaken for other skin conditions such as [[basal cell carcinoma]], [[squamous cell carcinoma]], or [[melanoma]]. | Porocarcinoma typically presents as a solitary, slow-growing [[nodule]] or [[plaque]] that may be [[ulcerated]] or [[bleeding]]. The lesion can vary in color, appearing as red, pink, or brown. Due to its nonspecific appearance, porocarcinoma can be mistaken for other skin conditions such as [[basal cell carcinoma]], [[squamous cell carcinoma]], or [[melanoma]]. | ||
== Pathophysiology == | == Pathophysiology == | ||
Porocarcinoma arises from the intraepidermal portion of the eccrine sweat glands. The exact cause of porocarcinoma is not well understood, but it is believed to be associated with [[genetic mutations]] and [[ultraviolet radiation]] exposure. The tumor cells exhibit atypical features and can invade surrounding tissues, leading to potential [[metastasis]]. | Porocarcinoma arises from the intraepidermal portion of the eccrine sweat glands. The exact cause of porocarcinoma is not well understood, but it is believed to be associated with [[genetic mutations]] and [[ultraviolet radiation]] exposure. The tumor cells exhibit atypical features and can invade surrounding tissues, leading to potential [[metastasis]]. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of porocarcinoma is confirmed through a [[biopsy]] and [[histopathological]] examination. Under the microscope, porocarcinoma is characterized by atypical cells with ductal differentiation. The presence of [[ductal structures]] and [[infiltrative growth]] patterns are key features in distinguishing porocarcinoma from other skin malignancies. | The diagnosis of porocarcinoma is confirmed through a [[biopsy]] and [[histopathological]] examination. Under the microscope, porocarcinoma is characterized by atypical cells with ductal differentiation. The presence of [[ductal structures]] and [[infiltrative growth]] patterns are key features in distinguishing porocarcinoma from other skin malignancies. | ||
== Treatment == | == Treatment == | ||
The primary treatment for porocarcinoma is [[surgical excision]] with clear margins. [[Mohs micrographic surgery]] is often employed to ensure complete removal of the tumor while preserving healthy tissue. In cases where the tumor has metastasized, additional treatments such as [[radiation therapy]] or [[chemotherapy]] may be considered. | The primary treatment for porocarcinoma is [[surgical excision]] with clear margins. [[Mohs micrographic surgery]] is often employed to ensure complete removal of the tumor while preserving healthy tissue. In cases where the tumor has metastasized, additional treatments such as [[radiation therapy]] or [[chemotherapy]] may be considered. | ||
== Prognosis == | == Prognosis == | ||
The prognosis for porocarcinoma depends on the stage at diagnosis and the presence of metastasis. Early detection and complete surgical removal generally result in a favorable outcome. However, advanced cases with regional or distant metastasis have a poorer prognosis. | The prognosis for porocarcinoma depends on the stage at diagnosis and the presence of metastasis. Early detection and complete surgical removal generally result in a favorable outcome. However, advanced cases with regional or distant metastasis have a poorer prognosis. | ||
== See Also == | |||
== | |||
* [[Eccrine sweat gland]] | * [[Eccrine sweat gland]] | ||
* [[Skin cancer]] | * [[Skin cancer]] | ||
| Line 32: | Line 34: | ||
* [[Squamous cell carcinoma]] | * [[Squamous cell carcinoma]] | ||
* [[Melanoma]] | * [[Melanoma]] | ||
{{Skin neoplasms}} | {{Skin neoplasms}} | ||
[[Category:Skin neoplasms]] | [[Category:Skin neoplasms]] | ||
[[Category:Rare cancers]] | [[Category:Rare cancers]] | ||
Latest revision as of 06:40, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Porocarcinoma | |
|---|---|
| |
| Synonyms | Malignant eccrine poroma, eccrine porocarcinoma |
| Pronounce | N/A |
| Specialty | Dermatology, Oncology |
| Symptoms | Skin lesion, ulceration, bleeding |
| Complications | N/A |
| Onset | Typically in adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Genetic mutations, UV radiation |
| Risks | Sun exposure, immunosuppression |
| Diagnosis | Biopsy, histopathology |
| Differential diagnosis | Squamous cell carcinoma, basal cell carcinoma, melanoma |
| Prevention | N/A |
| Treatment | Surgical excision, radiation therapy, chemotherapy |
| Medication | N/A |
| Prognosis | Variable, depends on stage and treatment |
| Frequency | Rare |
| Deaths | N/A |
Porocarcinoma, also known as eccrine porocarcinoma, is a rare type of skin cancer that originates from the eccrine sweat glands. It is considered a malignant form of poroma, a benign sweat gland tumor. Porocarcinoma is most commonly found in the elderly population and can occur anywhere on the body, although it frequently appears on the lower extremities.
Clinical Presentation[edit]
Porocarcinoma typically presents as a solitary, slow-growing nodule or plaque that may be ulcerated or bleeding. The lesion can vary in color, appearing as red, pink, or brown. Due to its nonspecific appearance, porocarcinoma can be mistaken for other skin conditions such as basal cell carcinoma, squamous cell carcinoma, or melanoma.
Pathophysiology[edit]
Porocarcinoma arises from the intraepidermal portion of the eccrine sweat glands. The exact cause of porocarcinoma is not well understood, but it is believed to be associated with genetic mutations and ultraviolet radiation exposure. The tumor cells exhibit atypical features and can invade surrounding tissues, leading to potential metastasis.
Diagnosis[edit]
The diagnosis of porocarcinoma is confirmed through a biopsy and histopathological examination. Under the microscope, porocarcinoma is characterized by atypical cells with ductal differentiation. The presence of ductal structures and infiltrative growth patterns are key features in distinguishing porocarcinoma from other skin malignancies.
Treatment[edit]
The primary treatment for porocarcinoma is surgical excision with clear margins. Mohs micrographic surgery is often employed to ensure complete removal of the tumor while preserving healthy tissue. In cases where the tumor has metastasized, additional treatments such as radiation therapy or chemotherapy may be considered.
Prognosis[edit]
The prognosis for porocarcinoma depends on the stage at diagnosis and the presence of metastasis. Early detection and complete surgical removal generally result in a favorable outcome. However, advanced cases with regional or distant metastasis have a poorer prognosis.
