Lupus erythematosus panniculitis: Difference between revisions
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{{Infobox medical condition | |||
| name = Lupus erythematosus panniculitis | |||
| synonyms = Lupus profundus | |||
| field = [[Rheumatology]], [[Dermatology]] | |||
| symptoms = [[Subcutaneous]] nodules, [[skin]] [[ulceration]], [[pain]] | |||
| complications = [[Scarring]], [[lipodystrophy]] | |||
| onset = Variable | |||
| duration = Chronic | |||
| causes = [[Autoimmune disease]] | |||
| risks = [[Systemic lupus erythematosus]], [[female]] gender, [[genetic predisposition]] | |||
| diagnosis = [[Clinical examination]], [[skin biopsy]] | |||
| differential = [[Erythema nodosum]], [[panniculitis]], [[infectious panniculitis]] | |||
| treatment = [[Corticosteroids]], [[antimalarials]], [[immunosuppressants]] | |||
| prognosis = Variable, depends on severity and response to treatment | |||
| frequency = Rare | |||
}} | |||
'''Lupus erythematosus panniculitis''' (also known as '''Lupus panniculitis''' or '''Lupus profundus''') is a rare form of [[Lupus erythematosus|lupus]] that primarily affects the [[Adipose tissue|fat tissue]] under the skin. It is characterized by inflammation and degeneration of the subcutaneous fat layer. | '''Lupus erythematosus panniculitis''' (also known as '''Lupus panniculitis''' or '''Lupus profundus''') is a rare form of [[Lupus erythematosus|lupus]] that primarily affects the [[Adipose tissue|fat tissue]] under the skin. It is characterized by inflammation and degeneration of the subcutaneous fat layer. | ||
== Symptoms == | == Symptoms == | ||
The most common symptom of lupus erythematosus panniculitis is the presence of firm, deep-seated nodules or plaques in the skin, particularly in the areas of the buttocks, thighs, upper arms, and face. These lesions may be painful and can lead to atrophy and scarring. Other symptoms may include fatigue, joint pain, and fever. | The most common symptom of lupus erythematosus panniculitis is the presence of firm, deep-seated nodules or plaques in the skin, particularly in the areas of the buttocks, thighs, upper arms, and face. These lesions may be painful and can lead to atrophy and scarring. Other symptoms may include fatigue, joint pain, and fever. | ||
== Causes == | == Causes == | ||
The exact cause of lupus erythematosus panniculitis is unknown. However, it is believed to be an [[Autoimmune disease|autoimmune disorder]], where the body's immune system mistakenly attacks its own tissues. It is also associated with other forms of lupus, such as [[Systemic lupus erythematosus|systemic lupus erythematosus]] (SLE) and [[Discoid lupus erythematosus|discoid lupus erythematosus]] (DLE). | The exact cause of lupus erythematosus panniculitis is unknown. However, it is believed to be an [[Autoimmune disease|autoimmune disorder]], where the body's immune system mistakenly attacks its own tissues. It is also associated with other forms of lupus, such as [[Systemic lupus erythematosus|systemic lupus erythematosus]] (SLE) and [[Discoid lupus erythematosus|discoid lupus erythematosus]] (DLE). | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of lupus erythematosus panniculitis is often challenging due to its rarity and nonspecific clinical presentation. It is typically confirmed through a combination of clinical findings, laboratory tests, and skin biopsy. | Diagnosis of lupus erythematosus panniculitis is often challenging due to its rarity and nonspecific clinical presentation. It is typically confirmed through a combination of clinical findings, laboratory tests, and skin biopsy. | ||
== Treatment == | == Treatment == | ||
Treatment for lupus erythematosus panniculitis primarily involves managing symptoms and preventing complications. This may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarial drugs, corticosteroids, and immunosuppressive agents. | Treatment for lupus erythematosus panniculitis primarily involves managing symptoms and preventing complications. This may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarial drugs, corticosteroids, and immunosuppressive agents. | ||
== See also == | == See also == | ||
* [[Lupus erythematosus]] | * [[Lupus erythematosus]] | ||
* [[Autoimmune disease]] | * [[Autoimmune disease]] | ||
* [[Systemic lupus erythematosus]] | * [[Systemic lupus erythematosus]] | ||
* [[Discoid lupus erythematosus]] | * [[Discoid lupus erythematosus]] | ||
[[Category:Autoimmune diseases]] | [[Category:Autoimmune diseases]] | ||
[[Category:Lupus erythematosus]] | [[Category:Lupus erythematosus]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 03:27, 4 April 2025
| Lupus erythematosus panniculitis | |
|---|---|
| Synonyms | Lupus profundus |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Subcutaneous nodules, skin ulceration, pain |
| Complications | Scarring, lipodystrophy |
| Onset | Variable |
| Duration | Chronic |
| Types | N/A |
| Causes | Autoimmune disease |
| Risks | Systemic lupus erythematosus, female gender, genetic predisposition |
| Diagnosis | Clinical examination, skin biopsy |
| Differential diagnosis | Erythema nodosum, panniculitis, infectious panniculitis |
| Prevention | N/A |
| Treatment | Corticosteroids, antimalarials, immunosuppressants |
| Medication | N/A |
| Prognosis | Variable, depends on severity and response to treatment |
| Frequency | Rare |
| Deaths | N/A |
Lupus erythematosus panniculitis (also known as Lupus panniculitis or Lupus profundus) is a rare form of lupus that primarily affects the fat tissue under the skin. It is characterized by inflammation and degeneration of the subcutaneous fat layer.
Symptoms[edit]
The most common symptom of lupus erythematosus panniculitis is the presence of firm, deep-seated nodules or plaques in the skin, particularly in the areas of the buttocks, thighs, upper arms, and face. These lesions may be painful and can lead to atrophy and scarring. Other symptoms may include fatigue, joint pain, and fever.
Causes[edit]
The exact cause of lupus erythematosus panniculitis is unknown. However, it is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks its own tissues. It is also associated with other forms of lupus, such as systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE).
Diagnosis[edit]
Diagnosis of lupus erythematosus panniculitis is often challenging due to its rarity and nonspecific clinical presentation. It is typically confirmed through a combination of clinical findings, laboratory tests, and skin biopsy.
Treatment[edit]
Treatment for lupus erythematosus panniculitis primarily involves managing symptoms and preventing complications. This may include the use of nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarial drugs, corticosteroids, and immunosuppressive agents.
