Tilbroquinol: Difference between revisions

Latest revision as of 01:45, 20 February 2025

An overview of the antiparasitic drug Tilbroquinol

Tilbroquinol is an antiparasitic medication primarily used in the treatment of amoebiasis, an infection caused by the Entamoeba histolytica parasite. It is known for its effectiveness in eliminating the cyst and trophozoite forms of the parasite in the intestinal tract.

Mechanism of Action[edit]

Tilbroquinol works by interfering with the metabolic processes of the Entamoeba histolytica parasite. It disrupts the DNA synthesis and cellular respiration of the parasite, leading to its death. This action helps in clearing the infection from the gastrointestinal tract.

Pharmacokinetics[edit]

Tilbroquinol is administered orally and is absorbed in the gastrointestinal tract. It is distributed throughout the body and reaches high concentrations in the liver, where the Entamoeba histolytica often resides. The drug is metabolized in the liver and excreted primarily through the bile and feces.

Clinical Uses[edit]

Tilbroquinol is used in the treatment of:

It is often prescribed in combination with other antiparasitic agents to ensure the complete eradication of the parasite from the body.

Side Effects[edit]

Common side effects of Tilbroquinol include:

In rare cases, patients may experience allergic reactions such as rash, itching, or swelling.

Contraindications[edit]

Tilbroquinol should not be used in individuals with known hypersensitivity to the drug. Caution is advised in patients with liver disease or renal impairment.

Related Pages[edit]

Tilbroquinol
Tilbroquinol 3D Ball

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-'''Tilbroquinol''' is a medication used to treat [[amoebiasis]], a parasitic infection caused by the amoeba ''[[Entamoeba histolytica]]''. It is not commonly used in the United States, but is more frequently used in other countries, particularly in Asia.
+{{Short description|An overview of the antiparasitic drug Tilbroquinol}}
-== Mechanism of action ==
+'''Tilbroquinol''' is an [[antiparasitic]] medication primarily used in the treatment of [[amoebiasis]], an infection caused by the [[Entamoeba histolytica]] parasite. It is known for its effectiveness in eliminating the [[cyst]] and [[trophozoite]] forms of the parasite in the [[intestinal tract]].
-Tilbroquinol works by inhibiting the growth of the amoeba ''Entamoeba histolytica'', thereby preventing it from causing infection. The exact mechanism of action is not fully understood, but it is believed to involve disruption of the amoeba's cellular processes.
-== Uses ==
+==Mechanism of Action==
-Tilbroquinol is primarily used to treat amoebiasis, but it may also be used to treat other parasitic infections. It is not a first-line treatment, but may be used when other treatments are ineffective or contraindicated.
+Tilbroquinol works by interfering with the [[metabolic processes]] of the [[Entamoeba histolytica]] parasite. It disrupts the [[DNA synthesis]] and [[cellular respiration]] of the parasite, leading to its death. This action helps in clearing the infection from the [[gastrointestinal tract]].
-== Side effects ==
+==Pharmacokinetics==
-Common side effects of tilbroquinol include nausea, vomiting, and abdominal pain. Less common side effects may include headache, dizziness, and skin rash. Severe side effects are rare, but may include severe allergic reactions.
+Tilbroquinol is administered orally and is absorbed in the [[gastrointestinal tract]]. It is distributed throughout the body and reaches high concentrations in the [[liver]], where the [[Entamoeba histolytica]] often resides. The drug is metabolized in the liver and excreted primarily through the [[bile]] and [[feces]].
-== Contraindications ==
+==Clinical Uses==
-Tilbroquinol should not be used in individuals with a known hypersensitivity to the drug. It should also be used with caution in individuals with liver or kidney disease, as these conditions may affect the body's ability to metabolize and eliminate the drug.
+Tilbroquinol is used in the treatment of:
+* [[Amoebic dysentery]]
+* [[Amoebic liver abscess]]
+* [[Intestinal amoebiasis]]
-== Interactions ==
+It is often prescribed in combination with other antiparasitic agents to ensure the complete eradication of the parasite from the body.
-Tilbroquinol may interact with other medications, including other antiparasitic drugs. It is important to inform your healthcare provider of all medications you are currently taking to avoid potential interactions.
-== See also ==
+==Side Effects==
+Common side effects of Tilbroquinol include:
+* [[Nausea]]
+* [[Vomiting]]
+* [[Diarrhea]]
+* [[Abdominal pain]]
+In rare cases, patients may experience [[allergic reactions]] such as [[rash]], [[itching]], or [[swelling]].
+==Contraindications==
+Tilbroquinol should not be used in individuals with known [[hypersensitivity]] to the drug. Caution is advised in patients with [[liver disease]] or [[renal impairment]].
+==Related Pages==
 * [[Amoebiasis]]
+* [[Antiparasitic drugs]]
 * [[Entamoeba histolytica]]
-* [[Antiparasitic drugs]]
+* [[Gastrointestinal tract infections]]
-[[Category:Medications]]
+[[Category:Antiparasitic agents]]
-[[Category:Antiparasitic drugs]]
+[[Category:Drugs used in amoebiasis]]
-{{stub}}
 <gallery>
-File:Tilbroquinol tilbroquinol.png
+File:tilbroquinol.png|Tilbroquinol
-File:Tilbroquinol_3D_ball.png
+File:Tilbroquinol 3D ball.png|Tilbroquinol 3D Ball
 </gallery>