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Ensulizole
{{Short description|A chemical compound used in sunscreens}}
{{DISPLAYTITLE:Ensulizole}}


Ensulizole, also known as phenylbenzimidazole sulfonic acid, is a chemical compound commonly used in sunscreens and other personal care products. It is a broad-spectrum ultraviolet (UV) filter that primarily absorbs UVB radiation, protecting the skin from harmful effects of the sun.
==Overview==
[[File:Ensulizole.svg|thumb|right|Structural formula of Ensulizole]]
'''Ensulizole''', also known by its chemical name phenylbenzimidazole sulfonic acid, is an organic compound commonly used in [[sunscreen]] products. It is known for its ability to absorb [[ultraviolet]] (UV) radiation, particularly in the UVB range, which is responsible for causing sunburn and contributing to [[skin cancer]].


== Properties and Mechanism of Action ==
==Chemical Properties==
Ensulizole is a white crystalline powder that is soluble in water and organic solvents. It is stable under normal conditions and does not degrade easily when exposed to light or heat. This makes it an ideal ingredient for sunscreens, as it provides long-lasting protection against UV radiation.
Ensulizole is a water-soluble compound, which makes it unique among many other sunscreen agents that are typically oil-soluble. Its solubility in water allows for the formulation of lightweight, non-greasy sunscreen products. The chemical structure of Ensulizole includes a benzimidazole ring, which is crucial for its UV-absorbing properties.


The mechanism of action of ensulizole involves the absorption of UVB radiation. When applied to the skin, it forms a thin film that acts as a barrier, preventing UVB rays from penetrating the skin. This helps to prevent sunburn and reduces the risk of skin cancer caused by excessive sun exposure.
==Mechanism of Action==
Ensulizole works by absorbing UVB radiation and converting it into less harmful energy, such as heat. This process helps protect the skin from the damaging effects of UV radiation, including [[DNA]] damage and the formation of [[free radicals]].


== Safety and Regulatory Status ==
==Usage in Sunscreens==
Ensulizole has been extensively tested for safety and is approved for use in sunscreens by regulatory authorities such as the U.S. Food and Drug Administration (FDA) and the European Union's Scientific Committee on Consumer Safety (SCCS). It has a long history of use in personal care products and has been found to be non-irritating and non-sensitizing to the skin.
Ensulizole is often used in combination with other [[sunscreen agents]] to provide broad-spectrum protection. It is particularly effective in protecting against UVB rays, which are primarily responsible for sunburn. Ensulizole is approved for use in many countries and is considered safe for use in cosmetic products.


However, like all chemical compounds, ensulizole should be used in accordance with the instructions provided by the manufacturer. It is important to apply sunscreen generously and reapply it regularly, especially after swimming or sweating, to maintain its effectiveness.
==Safety and Regulations==
Ensulizole is generally regarded as safe when used as directed in sunscreen products. Regulatory agencies, such as the [[Food and Drug Administration]] (FDA) in the United States and the European Commission, have evaluated its safety and efficacy. It is important for consumers to follow the instructions on sunscreen products to ensure adequate protection.


== Environmental Impact ==
==Related pages==
Ensulizole is considered to have a low environmental impact. It is not persistent in the environment and does not bioaccumulate in organisms. Studies have shown that it does not pose a significant risk to aquatic life when used as directed.
 
== Alternatives and Complementary Ingredients ==
Ensulizole is often used in combination with other UV filters to provide broad-spectrum protection against both UVA and UVB radiation. Commonly used complementary ingredients include avobenzone, octocrylene, and titanium dioxide. These ingredients work together to enhance the overall sun protection factor (SPF) of the sunscreen product.
 
== References ==
1. U.S. Food and Drug Administration. (2020). Sunscreen: How to Help Protect Your Skin from the Sun. Retrieved from [https://www.fda.gov/drugs/understanding-over-counter-medicines/sunscreen-how-help-protect-your-skin-sun]
 
2. European Commission. (2015). Scientific Committee on Consumer Safety. Opinion on Ensulizole. Retrieved from [https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_191.pdf]
 
== See Also ==
* [[Sunscreen]]
* [[Sunscreen]]
* [[Ultraviolet radiation]]
* [[Ultraviolet radiation]]
* [[Skin cancer]]
* [[Skin cancer]]
* [[Free radicals]]


[[Category:Chemical compounds]]
[[Category:Sunscreening agents]]
[[Category:Sunscreen ingredients]]
[[Category:Organic compounds]]
[[Category:Personal care products]]

Latest revision as of 03:37, 13 February 2025

A chemical compound used in sunscreens



Overview[edit]

Structural formula of Ensulizole

Ensulizole, also known by its chemical name phenylbenzimidazole sulfonic acid, is an organic compound commonly used in sunscreen products. It is known for its ability to absorb ultraviolet (UV) radiation, particularly in the UVB range, which is responsible for causing sunburn and contributing to skin cancer.

Chemical Properties[edit]

Ensulizole is a water-soluble compound, which makes it unique among many other sunscreen agents that are typically oil-soluble. Its solubility in water allows for the formulation of lightweight, non-greasy sunscreen products. The chemical structure of Ensulizole includes a benzimidazole ring, which is crucial for its UV-absorbing properties.

Mechanism of Action[edit]

Ensulizole works by absorbing UVB radiation and converting it into less harmful energy, such as heat. This process helps protect the skin from the damaging effects of UV radiation, including DNA damage and the formation of free radicals.

Usage in Sunscreens[edit]

Ensulizole is often used in combination with other sunscreen agents to provide broad-spectrum protection. It is particularly effective in protecting against UVB rays, which are primarily responsible for sunburn. Ensulizole is approved for use in many countries and is considered safe for use in cosmetic products.

Safety and Regulations[edit]

Ensulizole is generally regarded as safe when used as directed in sunscreen products. Regulatory agencies, such as the Food and Drug Administration (FDA) in the United States and the European Commission, have evaluated its safety and efficacy. It is important for consumers to follow the instructions on sunscreen products to ensure adequate protection.

Related pages[edit]