Veno-occlusive disease
Veno-occlusive disease
Veno-occlusive disease (pronounced: /ˈviːnoʊ oʊˈkluːsɪv dɪˈziːz/), also known as hepatic veno-occlusive disease or sinusoidal obstruction syndrome, is a condition characterized by the blockage of small veins in the liver.
Etymology
The term "veno-occlusive disease" is derived from the Latin words "vena" meaning vein, "occludere" meaning to close up, and "disease" from the Old French "desaise" meaning lack of ease.
Definition
Veno-occlusive disease is a condition in which the small veins that carry blood out of the liver become blocked, leading to liver damage. This can result in symptoms such as jaundice, fluid build-up in the abdomen, and weight gain.
Symptoms
The symptoms of veno-occlusive disease can vary, but often include jaundice, ascites (fluid build-up in the abdomen), and weight gain. Other symptoms may include fatigue, nausea, and abdominal pain.
Causes
Veno-occlusive disease can be caused by a variety of factors, including certain medications, radiation therapy, and bone marrow transplantation. It can also be associated with certain conditions such as hematologic malignancies and congenital disorders.
Treatment
Treatment for veno-occlusive disease typically involves managing the symptoms and treating the underlying cause. This may include medications to reduce fluid build-up, blood transfusions, or in severe cases, liver transplantation.
Related Terms
- Hepatic veno-occlusive disease
- Sinusoidal obstruction syndrome
- Hematologic malignancies
- Congenital disorders
- Jaundice
- Ascites
External links
- Medical encyclopedia article on Veno-occlusive disease
- Wikipedia's article - Veno-occlusive disease
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