Valspodar
Valspodar (pronounced: val-SPŌ-dar) is a pharmacological agent classified under the category of P-glycoprotein inhibitors. It is primarily used in the field of oncology to enhance the efficacy of certain chemotherapeutic agents.
Etymology
The term 'Valspodar' is derived from the Latin roots 'val', meaning 'strong', and 'spodar', meaning 'to inhibit'. This is reflective of the drug's strong inhibitory action on P-glycoprotein.
Pharmacology
Valspodar is a potent inhibitor of P-glycoprotein, a protein that pumps various substances out of cells. Some cancer cells are resistant to chemotherapy because they have a lot of this protein. By inhibiting P-glycoprotein, Valspodar allows chemotherapeutic drugs to enter and kill cancer cells more effectively.
Clinical Use
In clinical settings, Valspodar is often used in combination with other chemotherapeutic agents to treat various types of cancer, including leukemia, lymphoma, and multiple myeloma. It is also being investigated for its potential use in treating other diseases, such as HIV and malaria.
Related Terms
See Also
External links
- Medical encyclopedia article on Valspodar
- Wikipedia's article - Valspodar
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