Thromboxane receptor
Thromboxane Receptor
The Thromboxane Receptor (pronounced: throm-box-ane re-cep-tor), often abbreviated as TP, is a protein that in humans is encoded by the TBXA2R gene.
Etymology
The term "Thromboxane" is derived from the word "Thrombus," which is the medical term for a blood clot, and "oxane," which refers to the chemical structure of the compound. The "receptor" part of the term refers to the protein's function as a receptor for thromboxane in the body.
Function
The Thromboxane receptor is one of the Prostaglandin receptors, which bind to the Thromboxane A2 (TXA2) molecule. This binding causes a series of reactions that lead to platelet aggregation, vasoconstriction, and proliferation of smooth muscle cells, all of which are important processes in blood clotting and wound healing.
Related Terms
- Thromboxane: A type of eicosanoid, which are signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs) that are similar in structure.
- Prostaglandin receptors: A group of receptors that bind to and are activated by prostaglandins.
- Vasoconstriction: The narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels.
- Platelet aggregation: The clumping together of platelets in the blood, a part of the sequence of events leading to the formation of a clot.
See Also
External links
- Medical encyclopedia article on Thromboxane receptor
- Wikipedia's article - Thromboxane receptor
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