Platelet aggregation

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Platelet Aggregation

Platelet aggregation (pronunciation: /ˈplætlɪt æɡrɪˈɡeɪʃən/) is a crucial process in the formation of a blood clot. It involves the clumping together of platelets in the blood under certain physiological or pathological conditions.

Etymology

The term 'platelet aggregation' is derived from the word 'platelet', which comes from the Greek word 'platys', meaning 'flat', and 'aggregation', which originates from the Latin 'aggregare', meaning 'to come together'.

Process

Platelet aggregation is initiated by the activation of platelets due to injury or damage to the blood vessels. This activation leads to a change in the shape of the platelets and the release of certain substances that promote further aggregation. The process is regulated by various factors, including ADP, thromboxane A2, and serotonin.

Related Terms

  • Blood clot: A clump of blood that has changed from a liquid to a gel-like or semisolid state.
  • Thrombosis: The formation of a blood clot inside a blood vessel, obstructing the flow of blood.
  • Hemostasis: The process of stopping bleeding.
  • Coagulation: The process by which blood changes from a liquid to a gel, forming a clot.
  • Thrombocytopenia: A condition characterized by abnormally low levels of platelets in the blood.
  • Antiplatelet drugs: Medications that prevent platelets from clumping together to form a clot.

See Also

External links

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