Small-blue-round-cell tumor
Small-blue-round-cell tumor
Small-blue-round-cell tumor (pronunciation: smôl blo͞o round sel to͞o′mər) is a descriptive term used in pathology to describe a type of neoplasm that appears small, blue (due to a thin cytoplasm and a hyperchromatic nucleus) and round when viewed under a microscope.
Etymology
The term "Small-blue-round-cell tumor" is derived from the appearance of the cells under a microscope. The cells are small, have a high nucleus to cytoplasm ratio (making them appear blue), and are round in shape.
Related Terms
- Neoplasm: An abnormal growth of tissue, which can be benign or malignant.
- Pathology: The study of disease, its causes, processes, development, and consequences.
- Cytoplasm: The material within a living cell, excluding the cell nucleus.
- Nucleus: The central and most important part of an object, movement, or group, forming the basis for its activity and growth, especially in a cell.
- Microscope: An instrument used to see objects that are too small to be seen by the naked eye.
Classification
Small-blue-round-cell tumors are a heterogeneous group of malignant neoplasms. They are commonly found in children and adolescents, but can also occur in adults. The classification of these tumors is complex and is based on their histological appearance, immunohistochemical profile, and genetic features. Some examples of small-blue-round-cell tumors include Ewing's sarcoma, neuroblastoma, Wilms' tumor, and rhabdomyosarcoma.
Diagnosis
Diagnosis of small-blue-round-cell tumors is challenging due to their similar appearance under the microscope. It often requires a combination of histopathology, immunohistochemistry, and molecular genetic studies.
Treatment
Treatment of small-blue-round-cell tumors typically involves a combination of surgery, chemotherapy, and radiation therapy. The choice of treatment depends on the specific type of tumor, its location, and the patient's overall health.
External links
- Medical encyclopedia article on Small-blue-round-cell tumor
- Wikipedia's article - Small-blue-round-cell tumor
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