RNA therapeutics
RNA Therapeutics
RNA therapeutics (pronounced: R-N-A therapeutics) is a rapidly evolving field of medicine that uses RNA-based drugs to treat diseases.
Etymology
The term "RNA therapeutics" is derived from the abbreviation RNA, which stands for Ribonucleic Acid, and the word "therapeutics", which refers to the treatment of disease.
Definition
RNA therapeutics involves the use of RNA molecules as drugs to treat various diseases. These RNA molecules can either be small interfering RNAs (siRNA) or messenger RNAs (mRNA). The RNA molecules are designed to target specific genes in the body, thereby altering the expression of those genes and potentially treating the disease.
History
The concept of RNA therapeutics was first proposed in the late 20th century, following the discovery of RNA interference (RNAi). This discovery led to the development of siRNA-based drugs, which are designed to silence specific genes in the body. More recently, the field of RNA therapeutics has expanded to include mRNA-based drugs, which are designed to increase the expression of specific genes.
Applications
RNA therapeutics has potential applications in a wide range of diseases, including cancer, genetic disorders, infectious diseases, and autoimmune diseases. For example, RNA therapeutics is being used to develop vaccines for diseases such as COVID-19. In addition, RNA therapeutics is being explored as a potential treatment for genetic disorders such as cystic fibrosis and Duchenne muscular dystrophy.
Related Terms
- siRNA
- mRNA
- RNAi
- Gene expression
- Genetic disorders
- Autoimmune diseases
- Cystic fibrosis
- Duchenne muscular dystrophy
External links
- Medical encyclopedia article on RNA therapeutics
- Wikipedia's article - RNA therapeutics
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