Neurotrophin-3

Neurotrophin-3

Neurotrophin-3 (pronounced: noo-roh-troh-fin three), often abbreviated as NT-3, is a protein that in humans is encoded by the NTF3 gene.

Etymology

The term "Neurotrophin" is derived from the Greek words "neuron" meaning nerve and "trophin" meaning nourishing. The number "3" signifies that it is the third of four identified neurotrophins.

Function

Neurotrophin-3 is a neurotrophic factor, in the neurotrophin family, which controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta.

Related Terms

• Neurotrophin
• Nerve growth factor
• Brain-derived neurotrophic factor
• Neuron
• Protein
• Gene

See Also

• Neurotrophin-4
• Neurotrophin-5
• Neurotrophin-6

External links

• Medical encyclopedia article on Neurotrophin-3
• Wikipedia's article - Neurotrophin-3

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