Neurotrophin-4
Neurotrophin-4 (pronounced: noo-roh-troh-fin-4), also known as NT-4 or NTF4, is a protein that in humans is encoded by the NTF4 gene.
Etymology
The term "Neurotrophin" is derived from the Greek words "neuron" meaning nerve and "trophe" meaning nourishment. The number "4" signifies that it is one of the four members of the neurotrophin family.
Function
Neurotrophin-4 is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both NGF (nerve growth factor) and BDNF (brain-derived neurotrophic factor). It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta.
Clinical Significance
Alterations in the levels of Neurotrophin-4 have been implicated in neurodegenerative disorders like Alzheimer's disease, Parkinson's disease, and Huntington's disease.
Related Terms
- Neurotrophin
- NGF (nerve growth factor)
- BDNF (brain-derived neurotrophic factor)
- Alzheimer's disease
- Parkinson's disease
- Huntington's disease
External links
- Medical encyclopedia article on Neurotrophin-4
- Wikipedia's article - Neurotrophin-4
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski