Movat's stain

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Movat's stain (pronounced: mo-vat's stain) is a histological stain used in pathology to visualize and differentiate various tissue components. It was named after the Canadian pathologist Henry Zoltan Movat who developed it in 1955.

Etymology

The term "Movat's stain" is derived from the name of its developer, Dr. Henry Zoltan Movat, a Canadian pathologist. The term "stain" in this context refers to the process of adding color to microscopic specimens to enhance visibility and differentiation of their structures.

Usage

Movat's stain is a pentachrome stain, meaning it uses five colors to differentiate various tissue components. It is particularly useful in the study of connective tissue, as it can distinguish between collagen, elastin, smooth muscle, mucin, and fibrin.

Procedure

The procedure for Movat's stain involves several steps, each using a different dye to stain a specific component of the tissue. The dyes used include Alcian blue, Verhoeff's stain, Crocein scarlet, Brilliant green, and Safranin.

Related Terms

  • Histology: The study of the microscopic structure of tissues.
  • Pathology: The study of disease, its causes, processes, development, and consequences.
  • Pentachrome stain: A type of stain that uses five colors to differentiate tissue components.
  • Connective tissue: A type of tissue that provides support and structure to other tissues and organs in the body.
  • Collagen: The main structural protein in the extracellular matrix in the various connective tissues in the body.
  • Elastin: A highly elastic protein in connective tissue that allows many tissues in the body to resume their shape after stretching or contracting.
  • Smooth muscle: A type of muscle tissue which is used by various systems to apply pressure to vessels and organs.
  • Mucin: A family of high molecular weight, heavily glycosylated proteins produced by epithelial tissues in most animals.
  • Fibrin: A fibrous, non-globular protein involved in the clotting of blood.

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