Laudanosine
Laudanosine
Laudanosine (/lɔːˈdænəsiːn/) is a Benzylisoquinoline alkaloid that is found in various plants, including the Papaver somniferum (opium poppy) and Corydalis species. It is a byproduct of the metabolism of Atracurium and Cisatracurium, two commonly used neuromuscular blocking agents in anesthesia.
Etymology
The term "Laudanosine" is derived from the Latin laudare, meaning "to praise", and -osine, a common suffix used in the naming of alkaloids.
Pharmacology
Laudanosine is a Neurotoxin that has been shown to cause convulsions and hypotension in animals. It is also a Serotonin receptor antagonist and a weak Local anesthetic. Its potential effects on humans are not well-studied, but it is generally considered to be of low toxicity.
Related Terms
- Benzylisoquinoline
- Papaver somniferum
- Corydalis
- Atracurium
- Cisatracurium
- Neuromuscular-blocking drug
- Neurotoxin
- Convulsion
- Hypotension
- Serotonin receptor antagonist
- Local anesthetic
External links
- Medical encyclopedia article on Laudanosine
- Wikipedia's article - Laudanosine
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