Glitazone
Glitazone
Glitazone (pronounced: gli-ta-zone), also known as thiazolidinediones, are a class of medications used in the treatment of Type 2 diabetes.
Etymology
The term "Glitazone" is derived from the chemical structure of these drugs, which contain a thiazolidine ring and a 2,4-thiazolidinedione moiety.
Usage
Glitazones work by reducing insulin resistance and are often used in combination with other diabetes medications such as metformin or a sulfonylurea. They are not used for Type 1 diabetes as they require some insulin production by the pancreas.
Types
There are several types of glitazones, including:
- Pioglitazone
- Rosiglitazone
- Troglitazone (withdrawn from the market due to hepatotoxicity)
Side Effects
Common side effects of glitazones include weight gain, fluid retention, and an increased risk of heart failure. They may also increase the risk of bone fractures and bladder cancer.
Related Terms
External links
- Medical encyclopedia article on Glitazone
- Wikipedia's article - Glitazone
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