Flavin-containing monooxygenase 3
Flavin-containing monooxygenase 3 (FMO3) is an enzyme that in humans is encoded by the FMO3 gene. It is part of the flavin-containing monooxygenase family of enzymes.
Pronunciation
The pronunciation of Flavin-containing monooxygenase 3 is: /ˈflævɪn kənˈteɪnɪŋ ˌmɒnəʊˈɒksɪdeɪs ˈθriː/
Etymology
The term "Flavin" is derived from Latin flavus, meaning "yellow". This is due to the yellow color of riboflavin, a type of flavin. "Monooxygenase" refers to the type of reaction the enzyme catalyzes, specifically the incorporation of one atom of oxygen into the organic substrate.
Function
FMO3 is an important enzyme in the metabolism of a wide variety of xenobiotics such as therapeutic drugs, dietary compounds, and environmental pollutants. It is primarily found in the liver and, to a lesser extent, in the kidney, lung, and intestine.
Related Terms
- Flavin: A group of organic compounds based on pteridine, formed by the conjugation of a ribityl side chain with a heterocyclic isoalloxazine.
- Monooxygenase: An enzyme that incorporates one hydroxyl group into its substrate by the oxidation of a pair of hydrogen atoms.
- Xenobiotics: Chemical substances that are not naturally produced or expected to be present within an organism.
- Metabolism: The set of life-sustaining chemical reactions in organisms.
See Also
- Flavin-containing monooxygenase
- Flavin-containing monooxygenase 1
- Flavin-containing monooxygenase 2
- Flavin-containing monooxygenase 4
- Flavin-containing monooxygenase 5
External links
- Medical encyclopedia article on Flavin-containing monooxygenase 3
- Wikipedia's article - Flavin-containing monooxygenase 3
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