Clotting
Clotting
Clotting (pronunciation: /ˈklɒtɪŋ/), also known as coagulation, is a complex process by which the blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel.
Etymology
The term "clotting" comes from the Old English word "clott", meaning a lump or mass, and the process suffix "-ing". The term "coagulation" comes from the Latin "coagulare", meaning "to cause to curdle".
Process
Clotting involves a series of chemical reactions that result in the formation of a clot. The process begins with a platelet plug formation, followed by the coagulation cascade, which involves both the intrinsic and extrinsic pathways. The final product of the coagulation cascade is the fibrin clot.
Related Terms
- Hemostasis: The process of stopping the flow of blood to prevent excessive bleeding.
- Platelet: A type of blood cell that plays a major role in blood clotting.
- Coagulation factors: Proteins in the blood that work together to make a clot.
- Fibrin: A protein that forms a network of fibers during clotting to create a stable clot.
- Thrombus: A blood clot that forms in a blood vessel and remains there.
- Anticoagulant: A substance that prevents or reduces coagulation of the blood, prolonging the clotting time.
See Also
External links
- Medical encyclopedia article on Clotting
- Wikipedia's article - Clotting
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