Platelet plug

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Platelet Plug

A Platelet Plug (pronounced: /ˈplætlɪt plʌg/) is a crucial component in the hemostasis process, which is the cessation of blood loss from a damaged vessel.

Etymology

The term "Platelet Plug" is derived from the words "platelet", which comes from the Greek word "platys" meaning flat, and "plug", which is of Dutch origin, meaning "block or stopper".

Definition

A Platelet Plug is a mass of platelets that form at the site of a damaged blood vessel to prevent bleeding. It is the second step in the process of hemostasis, following vasoconstriction. The platelets change shape from spherical to stellate, and release the contents of their granules. These granules contain substances such as ADP, thromboxane A2, and serotonin, which, in turn, signal more platelets to help in the plug formation.

Related Terms

  • Hemostasis: The process of stopping blood flow.
  • Platelets: Small, colorless cell fragments in our blood that form clots and stop or prevent bleeding.
  • Vasoconstriction: The narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels.
  • ADP: Adenosine diphosphate, a crucial organic compound in metabolism used to store and release energy.
  • Thromboxane A2: A type of thromboxane that is produced by platelets during hemostasis.
  • Serotonin: A hormone that stabilizes our mood, feelings of well-being, and happiness.

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