Cariprazine
Cariprazine (pronounced as kuh-rip-ruh-zeen) is an antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. It is sold under the brand name Vraylar in the United States and Reagila in Europe.
Etymology
The name "Cariprazine" is derived from a combination of parts of the words "car" and "prazine", which are common components in the names of antipsychotic drugs.
Usage
Cariprazine is used for the treatment of schizophrenia and for the acute treatment of manic or mixed episodes associated with bipolar I disorder. It is also being investigated for use in the treatment of major depressive disorder.
Mechanism of Action
Cariprazine acts as a partial agonist at the dopamine D2 and D3 receptors, and at the serotonin 5-HT1A receptors. It also acts as an antagonist at the 5-HT2A receptors and the histamine H1 receptors.
Side Effects
Common side effects of cariprazine include insomnia, akathisia, weight gain, and nausea. Serious side effects may include tardive dyskinesia, neuroleptic malignant syndrome, and increased risk of suicide.
Related Terms
- Antipsychotic
- Schizophrenia
- Bipolar disorder
- Dopamine
- Serotonin
- Histamine
- Insomnia
- Akathisia
- Tardive dyskinesia
- Neuroleptic malignant syndrome
External links
- Medical encyclopedia article on Cariprazine
- Wikipedia's article - Cariprazine
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