Burapitant
Burapitant
Burapitant (pronounced as bur-uh-pi-tant) is a potent and selective neurokinin 1 receptor antagonist used in the treatment of chemotherapy-induced nausea and vomiting (CINV).
Etymology
The term "Burapitant" is derived from the chemical name of the drug, which is "Butyl-rapamycin-piperidine-tetrazole". Each part of the name represents a different component of the drug's chemical structure.
Usage
Burapitant is used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of cancer chemotherapy, including high-dose cisplatin.
Mechanism of Action
Burapitant works by blocking the actions of substance P/neurokinin 1 in the brain, which reduces the urge to vomit. It is often used in combination with other medications to prevent nausea and vomiting caused by cancer drug treatment and surgery.
Related Terms
- Neurokinin 1 receptor
- Chemotherapy-induced nausea and vomiting
- Cancer chemotherapy
- Cisplatin
- Substance P
External links
- Medical encyclopedia article on Burapitant
- Wikipedia's article - Burapitant
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