Bone marrow-derived macrophage
Bone marrow-derived macrophage
Bone marrow-derived macrophages (BMDMs) are a type of macrophage that originate from bone marrow stem cells. Pronunciation: /boʊn ˈmær.oʊ dɪˈraɪvd ˌmækroʊˈfeɪdʒ/
Etymology
The term "bone marrow-derived macrophage" is derived from the location of their origin (the bone marrow) and their function (as macrophages). The term "macrophage" itself comes from the Greek words "makros" (meaning "large") and "phagein" (meaning "to eat"), referring to the cell's ability to engulf and destroy pathogens.
Function
BMDMs play a crucial role in the body's immune system. They are responsible for engulfing and destroying pathogens, as well as presenting antigens to T cells to initiate an immune response. BMDMs are also involved in tissue repair and the regulation of inflammation.
Related Terms
- Macrophage: A type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, and cancer cells in a process called phagocytosis.
- Bone marrow: The soft, spongy tissue that fills the cavities of bones. Bone marrow is the source of all blood cells, including BMDMs.
- T cells: A type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
- Immune system: The body's defense against infectious organisms and other invaders. It is made up of a network of cells, tissues, and organs.
See Also
External links
- Medical encyclopedia article on Bone marrow-derived macrophage
- Wikipedia's article - Bone marrow-derived macrophage
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