Allenestrol
Allenestrol
Allenestrol (pronounced: al-len-es-trol), also known as ethamoxytriphetol, is a synthetic, nonsteroidal estrogen that was used in the past for a variety of estrogen-responsive conditions. It is no longer marketed and has been largely superseded by newer and safer drugs.
Etymology
The term "Allenestrol" is derived from the name of the scientist who first synthesized it, Dr. George W. Allen, and the Greek word "oistros", which means "gadfly" or "frenzy", and is the root of the word "estrogen".
Usage
Allenestrol was used primarily in the treatment of menopausal symptoms and disorders of the reproductive system. It was also used in the prevention of osteoporosis and in the treatment of certain types of breast cancer.
Pharmacology
Allenestrol, like other synthetic estrogens, works by binding to and activating the estrogen receptor, which then modulates the transcription of specific genes.
Side Effects
Potential side effects of Allenestrol include nausea, vomiting, breast tenderness, menstrual irregularities, and an increased risk of thromboembolism and endometrial cancer.
Related Terms
External links
- Medical encyclopedia article on Allenestrol
- Wikipedia's article - Allenestrol
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