Wooden chest syndrome
Wooden Chest Syndrome is a rare but serious condition characterized by severe chest wall rigidity and respiratory distress following the administration of certain opioids, most notably fentanyl. This condition is of particular concern in the fields of anesthesiology and emergency medicine.
Pathophysiology
Wooden Chest Syndrome is primarily associated with the administration of fentanyl, a potent synthetic opioid. The exact mechanism is not fully understood, but it is believed that fentanyl and similar opioids can cause increased muscle tone in the chest wall muscles, leading to rigidity. This rigidity can severely impair the ability of the chest to expand during inspiration, resulting in respiratory distress and potentially respiratory failure.
Clinical Presentation
Patients with Wooden Chest Syndrome typically present with sudden onset of:
- Chest wall rigidity
 - Respiratory distress
 - Difficulty in ventilation
 
These symptoms can occur within minutes of opioid administration, especially when given rapidly or in high doses.
Diagnosis
The diagnosis of Wooden Chest Syndrome is primarily clinical, based on the history of recent opioid administration and the characteristic presentation of chest wall rigidity and respiratory distress. It is important to differentiate this condition from other causes of respiratory distress, such as bronchospasm or pulmonary edema.
Management
The management of Wooden Chest Syndrome involves:
- Immediate cessation of opioid administration
 - Administration of naloxone, an opioid antagonist, which can rapidly reverse the effects of opioids
 - Supportive care, including oxygen therapy and, if necessary, mechanical ventilation
 
Prevention
To prevent Wooden Chest Syndrome, it is recommended to:
- Administer opioids slowly, especially potent ones like fentanyl
 - Use the lowest effective dose
 - Monitor patients closely for signs of respiratory distress
 
Prognosis
With prompt recognition and treatment, the prognosis for Wooden Chest Syndrome is generally good. However, delayed treatment can lead to significant complications, including hypoxia and cardiac arrest.
See Also
External Links
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Contributors: Prab R. Tumpati, MD