Wegener
Wegener's Granulomatosis
Wegener's Granulomatosis (pronounced: VAY-gen-erz gran-yuh-low-muh-TOE-sis), also known as Granulomatosis with polyangiitis (GPA), is a rare type of autoimmune disease that causes inflammation of the blood vessels (vasculitis).
Etymology
The condition is named after the German pathologist Friedrich Wegener, who first described the disease in 1936. The term "granulomatosis" refers to the formation of granulomas, which are clusters of immune cells that form in response to chronic inflammation. "Polyangiitis" refers to the inflammation of multiple blood vessels.
Symptoms
Symptoms of Wegener's Granulomatosis can vary greatly depending on the organs affected, but common symptoms include fatigue, weight loss, fever, night sweats, shortness of breath, and blood in the urine (hematuria).
Diagnosis
Diagnosis of Wegener's Granulomatosis typically involves a combination of blood tests, imaging studies such as CT scans or MRI, and tissue biopsy.
Treatment
Treatment for Wegener's Granulomatosis typically involves medications to reduce inflammation and suppress the immune system, such as corticosteroids and immunosuppressive drugs. In severe cases, chemotherapy may be used.
Prognosis
With treatment, the prognosis for Wegener's Granulomatosis is generally good, although the disease can cause serious complications if left untreated, including kidney failure and lung damage.
See Also
External links
- Medical encyclopedia article on Wegener
- Wikipedia's article - Wegener
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