WNT7B

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Ideogram human chromosome 22

WNT7B

WNT7B is a gene that encodes a member of the Wnt signaling pathway proteins. This gene is part of the Wnt family of proteins that play crucial roles in various developmental processes in organisms.

Function

The WNT7B protein is involved in cell signaling pathways that regulate cell growth, differentiation, and development. It is known to be important in embryogenesis, particularly in the development of various tissues and organs.

Role in Development

During embryonic development, WNT7B is expressed in specific regions where it plays a critical role in the formation of various structures. Studies have shown that mutations in the WNT7B gene can lead to developmental abnormalities and defects in organogenesis.

Clinical Significance

Aberrant expression of WNT7B has been associated with various diseases, including certain types of cancer. Research is ongoing to understand the precise mechanisms by which WNT7B contributes to disease pathogenesis.

Interactions

WNT7B interacts with several other proteins in the Wnt signaling pathway to regulate cellular processes. These interactions are essential for the proper functioning of the pathway and its downstream effects on gene expression.

References

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Contributors: Prab R. Tumpati, MD