WHO AWaRe

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Classification system for antibiotics by the World Health Organization



The World Health Organization (WHO) developed the AWaRe classification to guide antibiotic use.

The WHO AWaRe (Access, Watch, and Reserve) classification is a tool developed by the World Health Organization (WHO) to categorize antibiotics into three groups: Access, Watch, and Reserve. This classification aims to improve the use of antibiotics and combat antimicrobial resistance (AMR) by guiding healthcare providers in selecting the most appropriate antibiotic for specific infections.

Overview

The AWaRe classification was introduced by the WHO to address the growing concern of antimicrobial resistance, which poses a significant threat to global health. The classification system is designed to optimize the use of antibiotics, ensuring that they are used appropriately and effectively to treat infections while minimizing the risk of resistance development.

Classification

The AWaRe system divides antibiotics into three categories:

Access

The Access group includes antibiotics that are recommended as first or second choice for the treatment of common infections. These antibiotics are generally effective, have a lower risk of resistance, and are widely available. The goal is to ensure that these antibiotics are accessible to all who need them.

Watch

The Watch group consists of antibiotics that have a higher potential for resistance and should be used with caution. These antibiotics are recommended as first or second choice only for specific, limited indications. The use of Watch antibiotics should be closely monitored to prevent the development of resistance.

Reserve

The Reserve group includes antibiotics that should be considered last-resort options. These are used for the treatment of multi-drug resistant infections and should be preserved for cases where other antibiotics have failed. The use of Reserve antibiotics is highly restricted to prevent the emergence of resistance.

Implementation

The implementation of the AWaRe classification involves integrating it into national and local guidelines for antibiotic use. Healthcare providers are encouraged to follow the AWaRe guidelines to ensure the rational use of antibiotics. The WHO also provides support to countries in developing policies and strategies to promote the appropriate use of antibiotics.

Impact

The AWaRe classification has been instrumental in raising awareness about the importance of responsible antibiotic use. By categorizing antibiotics based on their potential for resistance, the system helps healthcare providers make informed decisions, ultimately contributing to the global effort to combat antimicrobial resistance.

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Contributors: Prab R. Tumpati, MD