Vertical transmission
Vertical transmission is the transmission of an infection or disease from the parent to the offspring. This can occur either during pregnancy, childbirth, or breastfeeding. Vertical transmission is a critical aspect of infectious diseases and genetic disorders.
Types of Vertical Transmission
Vertical transmission can be classified into two types: prenatal and postnatal.
Prenatal
Prenatal vertical transmission occurs when the mother passes the infection or disease to the fetus during pregnancy. This can happen through the placenta, a temporary organ that connects the mother and fetus, allowing for the exchange of nutrients, waste, and gases.
Postnatal
Postnatal vertical transmission occurs after birth, typically through breastfeeding. The mother can pass the infection or disease to the infant through her breast milk.
Diseases Transmitted Vertically
Several diseases can be transmitted vertically, including:
- Human Immunodeficiency Virus (HIV): This virus can be transmitted from the mother to the child during pregnancy, childbirth, or breastfeeding.
 - Hepatitis B Virus (HBV): This virus can be transmitted from the mother to the child during childbirth.
 - Zika Virus: This virus can be transmitted from the mother to the fetus during pregnancy.
 - Syphilis: This bacterial infection can be transmitted from the mother to the fetus during pregnancy.
 
Prevention
Prevention of vertical transmission is crucial to reduce the incidence of these diseases. This can be achieved through:
- Routine screening of pregnant women for these infections.
 - Treatment of infected mothers to reduce the risk of transmission.
 - Vaccination of infants immediately after birth.
 
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Contributors: Prab R. Tumpati, MD