Vadimezan

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Vadimezan (pronounced vah-dih-MEH-zan) is a small molecule inhibitor that was developed for the treatment of cancer. It is also known by its chemical name, DMXAA (5,6-dimethylxanthenone-4-acetic acid).

Etymology

The name "Vadimezan" is a proprietary name given by the pharmaceutical company that developed it. The chemical name, DMXAA, is an abbreviation of the chemical structure of the drug.

Pharmacology

Vadimezan is a type of drug known as a vascular disrupting agent. It works by disrupting the blood vessels that supply tumors, causing the tumors to starve and die. It is not a chemotherapy drug, but it is often used in combination with chemotherapy to enhance its effects.

Clinical Trials

Vadimezan has been tested in several clinical trials for various types of cancer, including lung cancer, melanoma, and kidney cancer. However, it has not yet been approved by the Food and Drug Administration (FDA) for use in the United States.

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