UroVysion

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UroVysion

UroVysion (pronounced: u-ro-vi-sion) is a diagnostic test used primarily in the field of urology to detect bladder cancer in urine samples. The test uses Fluorescence In Situ Hybridization (FISH) technology to identify chromosomal abnormalities associated with bladder cancer.

Etymology

The term "UroVysion" is a combination of "uro", derived from the Greek word "ouron" meaning urine, and "vision", referring to the visual examination of cells under a microscope. The name reflects the test's purpose of visually examining urine samples for signs of bladder cancer.

Procedure

The UroVysion test involves the collection of a urine sample, which is then examined using FISH technology. This technology uses fluorescent probes to bind to specific DNA sequences in the cells present in the urine sample. The probes are designed to bind to sequences found in chromosomes 3, 7, 9, and 17, which are commonly abnormal in bladder cancer cells. If these abnormalities are detected, it may indicate the presence of bladder cancer.

Related Terms

  • Urology: The branch of medicine that focuses on the urinary tract and the male reproductive system.
  • Bladder Cancer: A type of cancer that begins in the cells of the bladder.
  • Fluorescence In Situ Hybridization (FISH): A molecular diagnostic technique that uses fluorescent probes to detect specific DNA sequences in cells.
  • Chromosome: A structure found in cells that contains genetic material.
  • DNA: The molecule that carries genetic information in living organisms.

External links

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