Typhidot
Typhidot
Typhidot (pronounced: /ˈtaɪfɪdɒt/) is a medical test consisting of a dot ELISA kit that detects IgM and IgG antibodies against the outer membrane protein (OMP) of the Salmonella typhi. The typhidot test becomes positive within 2-3 days of infection and separately identifies IgM and IgG antibodies.
Etymology
The term "Typhidot" is a combination of "Typhi" and "dot". "Typhi" is derived from Salmonella typhi, the bacterium that causes typhoid fever, and "dot" refers to the dot ELISA technique used in the test.
Procedure
The Typhidot test is conducted by adding a patient's serum to a test strip containing typhoid-specific antigens. If the patient has typhoid, antibodies in their serum will bind to the antigens, forming visible dots on the strip.
Interpretation
A positive Typhidot result indicates current or recent infection with Salmonella typhi. A positive IgM result indicates current infection, while a positive IgG result indicates past infection or immunity.
Related Terms
- Dot ELISA: A type of enzyme immunoassay that uses a dot blot technique for the detection of antibodies.
- IgM: The first antibody to appear in response to an initial exposure to an antigen.
- IgG: The most common type of antibody found in blood circulation.
- Salmonella typhi: A bacterium that causes typhoid fever.
- Typhoid fever: A systemic, febrile illness caused by Salmonella typhi.
External links
- Medical encyclopedia article on Typhidot
- Wikipedia's article - Typhidot
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