Tubular proteinuria
Tubular Proteinuria is a type of proteinuria that is characterized by the excretion of low molecular weight proteins in the urine. This condition is typically caused by a dysfunction of the renal tubules, which are responsible for reabsorbing these proteins back into the bloodstream.
Causes
Tubular proteinuria can be caused by a variety of conditions that affect the renal tubules. These include:
- Acute tubular necrosis
- Chronic kidney disease
- Diabetes mellitus
- Hypertension
- Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and some antibiotics
Symptoms
The symptoms of tubular proteinuria can vary depending on the underlying cause of the condition. However, some common symptoms include:
- Edema (swelling)
- Fatigue
- Foamy urine
- Unintentional weight loss
Diagnosis
Tubular proteinuria is typically diagnosed through a urine test, which can detect the presence of low molecular weight proteins. In some cases, a kidney biopsy may also be necessary to determine the underlying cause of the condition.
Treatment
The treatment for tubular proteinuria typically involves addressing the underlying cause of the condition. This may involve:
- Medications to control blood pressure or blood sugar levels
- Changes to the diet
- Dialysis or kidney transplant in severe cases
See Also
References
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Contributors: Prab R. Tumpati, MD