Trunk neural crest

Details
Synonyms
Pronunciation
Carnegie stage
Days
Precursor	Neural crest
Gives rise to
Part of

The trunk neural crest is a population of cells that originates from the neural crest during embryonic development. These cells are crucial for the formation of various structures in the body.

Development

The trunk neural crest cells emerge from the dorsal part of the neural tube and migrate to different parts of the embryo. They differentiate into a variety of cell types, including:

• Sensory neurons of the dorsal root ganglia
• Sympathetic neurons
• Schwann cells
• Melanocytes
• Cells of the adrenal medulla

Migration

Trunk neural crest cells follow specific migratory pathways to reach their destinations. These pathways are influenced by various molecular signals and extracellular matrix components.

Function

The trunk neural crest is essential for the development of the peripheral nervous system. It contributes to the formation of the autonomic nervous system, which regulates involuntary bodily functions.

Clinical Significance

Defects in trunk neural crest development can lead to various medical conditions, such as:

• Neuroblastoma
• Hirschsprung's disease
• Waardenburg syndrome

See Also

• Cranial neural crest
• Cardiac neural crest
• Neural crest cells

External Links

• Neural Crest on WikiMD