Trichomonas vaginalis
A protozoan parasite causing trichomoniasis
Trichomonas vaginalis is a protozoan parasite and the causative agent of trichomoniasis, a common sexually transmitted infection (STI) in humans. It is a flagellated anaerobic organism that primarily infects the urogenital tract.
Morphology
Trichomonas vaginalis is a pear-shaped organism with five flagella, four of which are anterior and one is posterior, aiding in its motility. It has an undulating membrane that extends about two-thirds of its body length. The organism is approximately 7 to 23 micrometers in length and 5 to 15 micrometers in width.
Life Cycle
The life cycle of Trichomonas vaginalis is relatively simple, consisting of a trophozoite stage only. It does not form cysts. The trophozoites multiply by binary fission and are transmitted from person to person primarily through sexual contact.
Pathogenesis
Trichomonas vaginalis infects the urogenital tract, causing inflammation and irritation. In women, it can lead to vaginitis, characterized by a frothy, yellow-green vaginal discharge with a strong odor, itching, and discomfort during urination or intercourse. In men, the infection is often asymptomatic but can cause urethritis.
Diagnosis
Diagnosis of Trichomonas vaginalis infection is typically made through microscopic examination of vaginal or urethral swabs. The organism can be identified by its characteristic motility. Other diagnostic methods include culture, antigen detection, and nucleic acid amplification tests (NAATs).
Treatment
The standard treatment for trichomoniasis is metronidazole or tinidazole, which are effective in eradicating the infection. It is important for sexual partners to be treated simultaneously to prevent reinfection.
Epidemiology
Trichomonas vaginalis is one of the most common non-viral STIs worldwide. It affects millions of people annually, with higher prevalence rates in women than in men. The infection is more common in certain populations, including those with multiple sexual partners and those with other STIs.
Prevention
Preventive measures include practicing safe sex, using condoms, and regular STI screenings. Educating individuals about the transmission and symptoms of trichomoniasis can also help reduce the spread of the infection.
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References
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