Transmissible gastroenteritis virus

02-0042-F1.E

Transmissible gastroenteritis virus (TGEV) is a highly contagious coronavirus that infects the intestines of swine, including domesticated pigs and wild boars. The virus is characterized by causing severe gastroenteritis, leading to high morbidity and mortality rates, especially in young piglets. This article provides an overview of TGEV, including its transmission, symptoms, diagnosis, prevention, and control measures.

Transmission

TGEV is primarily transmitted through the fecal-oral route. The virus is shed in the feces of infected animals and can contaminate feed, water, bedding, and the environment. It can also be spread by contaminated equipment, clothing, and personnel moving between infected and uninfected animals. The virus is highly infectious and can spread rapidly within and between swine herds.

Symptoms

The clinical signs of TGEV infection can vary depending on the age of the pigs and the virulence of the infecting virus strain. In neonatal piglets, the disease is often acute and severe, characterized by watery diarrhea, dehydration, and high mortality rates, often reaching 100% in piglets less than two weeks old. In older pigs, the symptoms may be milder, and affected animals often recover, although growth rates may be impacted.

Diagnosis

Diagnosis of TGEV is based on clinical signs, histopathological examination of the intestines, and detection of the virus or its genetic material. Techniques such as enzyme-linked immunosorbent assay (ELISA), polymerase chain reaction (PCR), and virus isolation can be used to confirm the presence of TGEV.

Prevention and Control

Prevention and control of TGEV infection are primarily based on biosecurity measures to prevent the introduction and spread of the virus. These measures include quarantine and testing of new animals before introduction to the herd, thorough cleaning and disinfection of facilities, and strict hygiene protocols for personnel and equipment. Vaccination of pregnant sows can also provide passive immunity to piglets through colostrum, offering some level of protection against the virus.

In some regions, exposure of the entire herd to a mild strain of the virus has been used as a method to induce herd immunity. However, this approach carries risks and should only be considered under specific circumstances and with professional veterinary guidance.

Conclusion

Transmissible gastroenteritis virus is a significant pathogen in the swine industry, causing considerable economic losses due to high mortality in piglets and reduced growth in surviving pigs. Effective management and control of TGEV require a comprehensive approach, including strict biosecurity measures, appropriate vaccination strategies, and good herd management practices. Ongoing research and development of new diagnostic tools and vaccines are crucial for improving the control of TGEV and reducing its impact on swine production.

   This article is a virus-related stub. You can help WikiMD by expanding it!